10.57647/j.ijc.2025.1502.21

Fabrication of nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4] as a novel magnetic nanocatalyst, and its utility for the construction of 1,2,4-triazolo[1,5-a]pyrimidines

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  • Abdolkarim Zare1,
  • Elham Jazinizadeh2,
  • Fatemeh Mostaghar2,
  • Habibeh Golchaman2,
  • Seyed Sajad Sajadikhah2,
  • Marziyeh Barzegar2,
  1. Department of Chemistry, Faculty of Nano and Bio Science and Technology, Persian Gulf University, Bushehr, Iran
  2. Department of Chemistry, Payame Noor University, Tehran, Iran
Fabrication of nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4] as a novel magnetic nanocatalyst, and its utility for the construction of 1,2,4-triazolo[1,5-a]pyrimidines

Received: 2024-12-10

Revised: 2025-05-01

Accepted: 2025-05-17

Published in Issue 2025-05-28

Copyright (c) -1 Abdolkarim Zare, Elham Jazinizadeh, Fatemeh Mostaghar, Habibeh Golchaman, Seyed Sajad Sajadikhah, Marziyeh Barzegar (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Zare, A., Jazinizadeh, E., Mostaghar, F., Golchaman, H., Sajadikhah, S. S., & Barzegar, M. (2025). Fabrication of nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4] as a novel magnetic nanocatalyst, and its utility for the construction of 1,2,4-triazolo[1,5-a]pyrimidines. Iranian Journal of Catalysis, 15(2 (June 2025). https://doi.org/10.57647/j.ijc.2025.1502.21
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Abstract

Nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4] (NFSPBF), as a novel magnetic nanomaterial, was fabricated, and its structure was corroborated using EDX, elemental mapping, FE-SEM, XRD, FT-IR, TG, and VSM analyses. In continuation, NFSPBF was employed as an efficacious catalyst for the one-pot multi-component reaction of acetoacetanilide, aryl aldehydes, and 3-amino-1,2,4-triazole to give 1,2,4-triazolo[1,5-a]pyrimidines in high yields (86-95%) and short times (10-15 min). NFSPBF could act as a dual-functional catalyst; FeCl4− of nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4] is a Lewis acid, and its pyridine moiety is a base. It was reusable for two times without a remarkable decrement in its catalytic performance.

Research Highlights

  1. Fabrication of nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4] as a novel magnetic nanocatalyst was introduced.
  2. Full characterization of the nanocatalyst was performed.
  3. Utility of the catalyst for the construction of 1,2,4-triazolo[1,5-a]pyrimidines was checked.
  4. Constructing 1,2,4-triazolo[1,5-a]pyrimidines in high yields and short times were obtained.
  5. Proposing a mechanism based on dual-functionality of the catalyst was provided.

Keywords

  • 3-Amino-1,2,4-triazole,
  • Dual-functional catalyst,
  • Magnetic nanomaterial,
  • Nano-[Fe3O4@SiO2@Si-Pr-Bipyr][FeCl4],
  • 1,2,4-Triazolo[1,5-a]pyrimidine
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