10.1007/s40097-021-00452-3

Efficient dye degradation, antimicrobial behavior and molecular docking analysis of gold (Au) and cellulose nanocrystals (CNC)-doped strontium oxide nanocomposites

  • Muhammad Ikram1,
  • Shahida Abbas2,
  • Ali Haider3,
  • Sadia Naz4,
  • S. O. A. Ahmad1,
  • Junaid Haider4,
  • Anwar Ul-Hamid*5,
  • Anum Shahzadi6,
  • Iram Shahzadi7,
  • Alvina Rafiq Butt1,
  1. Solar Cell Application Research Lab, Department of Physics, Government College University Lahore, Lahore, Punjab, 54000, PK
  2. Physics Department, Lahore Garrison University Lahore, Lahore, Punjab, 54000, PK
  3. Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore, Punjab, 54000, PK
  4. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, CN
  5. Core Research Facilities, Research Institute, King Fahd University of Petroleum and Minerals, Dhahran, 31261, SA
  6. Faculty of Pharmacy, The University of Lahore, Lahore, PK
  7. Punjab College of Pharmacy, University of the Punjab, Lahore, 54000, PK

Published in Issue 12-10-2021

How to Cite

Ikram, M., Abbas, S., Haider, A., Naz, S., Ahmad, S. O. A., Haider, J., Ul-Hamid, A., Shahzadi, A., Shahzadi, I., & Butt, A. R. (2021). Efficient dye degradation, antimicrobial behavior and molecular docking analysis of gold (Au) and cellulose nanocrystals (CNC)-doped strontium oxide nanocomposites. Journal of Nanostructure in Chemistry, 12(5 (October 2022). https://doi.org/10.1007/s40097-021-00452-3
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Abstract

Abstract Novel Au and cellulose nanocrystals (CNC)-doped SrO nanocomposites have been fabricated using simple and cost-effective chemical co-precipitation technique. Various concentrations of Au were doped into fixed amounts of CNC and SrO nanocomposites. The objective of this triplex nanocomposite was to examine the effect of incorporating dopants in SrO on the efficient elimination of organic contaminants from water and their antibacterial potential with molecular docking study. Adequate experimental conditions such as temperature, suitable volume ratio of reactants and pH were generated during the synthesis. For comparative studies, nanocomposites were evaluated through a number of characterization tools. The structural and morphological analysis through XRD and HR-TEM revealed the cubic crystalline structure of aggregated SrO quantum dots (QDs). Furthermore, an interconnected chain-like structure of nanoclusters was observed upon CNC and Au incorporation in SrO lattice. The size of nanoclusters/nanoparticles was calculated to be approximately 30 nm which matched well with the reported literature. Reduction in crystallinity and bandgap from 4.12 eV (for pristine SrO) to 3.8 eV was observed upon co-doping with CNC and Au in SrO lattice. Furthermore, pH-based catalytic analysis of prepared nanocomposites revealed 98% dye degradation (in acidic media) against methylene blue ciprofloxacin (MBCF) dye along with good bactericidal activities against Gram-positive/negative bacteria, respectively. In silico molecular docking analysis for enzyme targets belonging to cell wall synthesis (penicillin-binding protein 4) and fatty acid synthesis (enoyl-[acyl-carrier-protein] reductase) suggested Au–CNC and Au/CNC-doped SrO nanostructures as possible inhibitors of these enzymes owing to their good binding scores and binding interactions with active site residues. Graphic abstract (a) Preparation of cellulose nanocrystals (CNC) by acid hydrolysis. (b) Schematic synthesis route to fabricate Au/CNC–SrO nanocomposites.

Keywords

  • Quantum dots,
  • Nanoclusters,
  • Co-precipitation,
  • Cellulose nanocrystals,
  • Methylene Blue,
  • Ciprofloxacin,
  • E. coli,
  • S. aureus

References

  1. Srivastav (2020) Chemical fertilizers and pesticides: role in groundwater contamination (pp. 143-159) https://doi.org/10.1016/B978-0-08-103017-2.00006-4
  2. Zhao et al. (2016) Treatment of lead contaminated water by a PVDF membrane that is modified by zirconium, phosphate and PVA (pp. 564-573) https://doi.org/10.1016/j.watres.2016.04.078
  3. Mekonnen and Hoekstra (2016) Sustainability: Four billion people facing severe water scarcity https://doi.org/10.1126/sciadv.1500323
  4. Kummu et al. (2016) The world’s road to water scarcity: shortage and stress in the 20th century and pathways towards sustainability (pp. 1-16) https://doi.org/10.1038/srep38495
  5. Sharma and Bhattacharya (2017) Drinking water contamination and treatment techniques (pp. 1043-1067) https://doi.org/10.1007/s13201-016-0455-7
  6. Cambié et al. (2016) Applications of continuous-flow photochemistry in organic synthesis, material science, and water treatment (pp. 10276-10341) https://doi.org/10.1021/acs.chemrev.5b00707
  7. Abendrot et al. (2020) Zinc(II) complexes with amino acids for potential use in dermatology: synthesis, crystal structures, and antibacterial activity https://doi.org/10.3390/molecules25040951
  8. Milenkovic et al. (2017) Bactericidal activity of Cu-, Zn-, and Ag-containing zeolites toward Escherichia coli isolates (pp. 20273-20281) https://doi.org/10.1007/s11356-017-9643-8
  9. Duffy et al. (2018) Investigation into the antibacterial activity of silver, zinc oxide and copper oxide nanoparticles against poultry-relevant isolates of Salmonella and Campylobacter (pp. 293-300) https://doi.org/10.1016/j.foodcont.2018.05.008
  10. El-Shafiy et al. (2017) New nano-complexes of Zn(II), Cu(II), Ni(II) and Co(II) ions; spectroscopy, thermal, structural analysis, DFT calculations and antimicrobial activity application (pp. 452-461) https://doi.org/10.1016/j.molstruc.2017.06.121
  11. Lei et al. (2019) Fabrication of a novel antibacterial TPU nanofiber membrane containing Cu-loaded zeolite and its antibacterial activity toward Escherichia coli (pp. 11682-11693) https://doi.org/10.1007/s10853-019-03727-x
  12. Wadi et al. (2019) Linear sulfur-nylon composites: structure, morphology, and antibacterial activity (pp. 198-208) https://doi.org/10.1021/acsapm.9b00754
  13. Qais et al. (2019) Antibacterial effect of silver nanoparticles synthesized using Murraya koenigii (L.) against multidrug-resistant pathogens https://doi.org/10.1155/2019/4649506
  14. Palermo et al. (2019) Antibacterial activity of polymers: discussions on the nature of amphiphilic balance (pp. 3728-3731) https://doi.org/10.1002/ange.201813810
  15. Nowack et al. (2011) 120 years of nanosilver history: implications for policy makers (pp. 1177-1183) https://doi.org/10.1021/es103316q
  16. Ma et al. (2017) Titanium dioxide nanoparticles induce size-dependent cytotoxicity and genomic DNA hypomethylation in human respiratory cells (pp. 23560-23572) https://doi.org/10.1039/C6RA28272E
  17. Pichat (2010) A brief survey of the potential health risks of TiO2 particles and TiO2-containing photocatalytic or non-photocatalytic materials (pp. 238-246)
  18. Mohammad-Shahadat et al. (2012) Synthesis, characterization, photolytic degradation, electrical conductivity and applications of a nanocomposite adsorbent for the treatment of pollutants (pp. 7207-7220) https://doi.org/10.1039/c2ra20589k
  19. Li et al. (2021) S-doped TiO2 photocatalyst for visible LED mediated oxone activation: kinetics and mechanism study for the photocatalytic degradation of pyrimethanil fungicide https://doi.org/10.1016/j.cej.2021.128450
  20. Isari et al. (2020) N, Cu co-doped TiO2@functionalized SWCNT photocatalyst coupled with ultrasound and visible-light: an effective sono-photocatalysis process for pharmaceutical wastewaters treatment https://doi.org/10.1016/j.cej.2019.123685
  21. Nabi et al. (2011) Synthesis and characterization of polyanilineZr(IV)sulphosalicylate composite and its applications (1) electrical conductivity, and (2) antimicrobial activity studies (pp. 706-714) https://doi.org/10.1016/j.cej.2011.07.081
  22. Nagajyothi et al. (2019) Green synthesis: photocatalytic degradation of textile dyes using metal and metal oxide nanoparticles-latest trends and advancements (pp. 2617-2723) https://doi.org/10.1080/10643389.2019.1705103
  23. Bushra et al. (2014) Synthesis, characterization, antimicrobial activity and applications of polyanilineTi(IV)arsenophosphate adsorbent for the analysis of organic and inorganic pollutants (pp. 481-489) https://doi.org/10.1016/j.jhazmat.2013.09.044
  24. Shahadat et al. (2014) A comparative study for the characterization of polyaniline based nanocomposites and membrane properties (pp. 20686-20692) https://doi.org/10.1039/C4RA01040J
  25. Shahadat et al. (2015) Titanium-based nanocomposite materials: a review of recent advances and perspectives (pp. 121-137) https://doi.org/10.1016/j.colsurfb.2014.11.049
  26. Cheng et al. (2020) Enhanced photoelectrochemical and photocatalytic properties of anatase-TiO2(B) nanobelts decorated with CdS nanoparticles https://doi.org/10.1016/j.solidstatesciences.2019.106075
  27. Gusain et al. (2019) Adsorptive removal and photocatalytic degradation of organic pollutants using metal oxides and their composites: a comprehensive review https://doi.org/10.1016/j.cis.2019.102009
  28. Lu and Astruc (2020) Nanocatalysts and other nanomaterials for water remediation from organic pollutants https://doi.org/10.1016/j.ccr.2020.213180
  29. Chen et al. (2020) Photocatalytic degradation of organic pollutants using TiO2-based photocatalysts: A review https://doi.org/10.1016/j.jclepro.2020.121725
  30. Ahuja et al. (2021) Transition metal oxides and their composites for photocatalytic dye degradation https://doi.org/10.3390/jcs5030082
  31. Sultana et al. (2015) SnO2-SrO based nanocomposites and their photocatalytic activity for the treatment of organic pollutants (pp. 393-399) https://doi.org/10.1016/j.molstruc.2015.06.032
  32. Melinte et al. (2019) Polymer nanocomposites for photocatalytic applications https://doi.org/10.3390/catal9120986
  33. Tabah et al. (2017) Solar-heated sustainable biodiesel production from waste cooking oil using a sonochemically deposited SrO catalyst on microporous activated carbon (pp. 6228-6239) https://doi.org/10.1021/acs.energyfuels.7b00932
  34. Rahman et al. (2016) A novel approach towards hydrazine sensor development using SrO·CNT nanocomposites (pp. 65338-65348) https://doi.org/10.1039/C6RA11582A
  35. Saska et al. (2011) Bacterial cellulose-hydroxyapatite nanocomposites for bone regeneration https://doi.org/10.1155/2011/175362
  36. Elfeky et al. (2020) Multifunctional cellulose nanocrystal /metal oxide hybrid, photo-degradation, antibacterial and larvicidal activities https://doi.org/10.1016/j.carbpol.2019.115711
  37. Alavi and Nokhodchi (2020) An overview on antimicrobial and wound healing properties of ZnO nanobiofilms, hydrogels, and bionanocomposites based on cellulose, chitosan, and alginate polymers https://doi.org/10.1016/j.carbpol.2019.115349
  38. Elahi et al. (2018) Recent biomedical applications of gold nanoparticles: a review (pp. 537-556) https://doi.org/10.1016/j.talanta.2018.02.088
  39. Krishnaraj et al. (2014) Acalypha indica Linn: Biogenic synthesis of silver and gold nanoparticles and their cytotoxic effects against MDA-MB-231, human breast cancer cells (pp. 42-49) https://doi.org/10.1016/j.btre.2014.08.002
  40. Lizundia et al. (2018) Metal nanoparticles embedded in cellulose nanocrystal based films: material properties and post-use analysis (pp. 2618-2628) https://doi.org/10.1021/acs.biomac.8b00243
  41. Athar (2013) Synthesis and characterization of strontium oxide nanoparticles via wet process (pp. 450-453) https://doi.org/10.1166/mat.2013.1121
  42. Hati et al. (2017) Comparative growth behaviour and biofunctionality of lactic acid bacteria during fermentation of soy milk and bovine milk (pp. 277-283) https://doi.org/10.1007/s12602-017-9279-5
  43. Aqeel et al. (2020) Photocatalytic, dye degradation, and bactericidal behavior of Cu-doped ZnO nanorods and their molecular docking analysis (pp. 8314-8330) https://doi.org/10.1039/D0DT01397H
  44. Arularasu et al. (2020) Synthesis and characterization of cellulose/TiO2 nanocomposite: Evaluation of in vitro antibacterial and in silico molecular docking studies https://doi.org/10.1016/j.carbpol.2020.116868
  45. Alexander et al. (2018) Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus (pp. 19854-19865) https://doi.org/10.1074/jbc.RA118.004952
  46. Schiebel et al. (2014) Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor (pp. 15987-16005) https://doi.org/10.1074/jbc.M113.532804
  47. Abagyan and Totrov (1994) Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins (pp. 983-1002) https://doi.org/10.1006/jmbi.1994.1052
  48. Apsana et al. (2018) biomimetic synthesis and antibacterial properties of strontium oxide nanoparticles using ocimum sanctum leaf extract https://doi.org/10.22159/ajpcr.2018.v11i3.20858
  49. Tang et al. (2017) Anchoring 20(R)-Ginsenoside Rg3 onto Cellulose Nanocrystals to Increase the Hydroxyl Radical Scavenging Activity (pp. 7507-7513) https://doi.org/10.1021/acssuschemeng.6b02996
  50. Antonakos et al. (2007) Micro-Raman and FTIR studies of synthetic and natural apatites (pp. 3043-3054) https://doi.org/10.1016/j.biomaterials.2007.02.028
  51. Tjeerdsma and Militz (2005) Chemical changes in hydrothermal treated wood: FTIR analysis of combined hydrothermal and dry heat-treated wood (pp. 102-111) https://doi.org/10.1007/s00107-004-0532-8
  52. Boccuzzi and Chiorino (2000) FTIR study of CO oxidation on Au/TiO2 at 90 K and room temperature. An insight into the nature of the reaction centers (pp. 5414-5416) https://doi.org/10.1021/jp000749w
  53. Boccuzzi et al. (1996) FTIR study of carbon monoxide oxidation and scrambling at room temperature over gold supported on ZnO and TiO2 (pp. 3625-3631) https://doi.org/10.1021/jp952259n
  54. Chandran et al. (2006) Synthesis of gold nanotriangles and silver nanoparticles using aloe vera plant extract (pp. 577-583) https://doi.org/10.1021/bp0501423
  55. Yamashita (1994) Photoluminescence spectra of the Eu2+ center in SrO:Eu (pp. 195-199) https://doi.org/10.1016/0022-2313(94)90041-8
  56. Rhim et al. (2010) Changes in electrical and microstructural properties of microcrystalline cellulose as function of carbonization temperature (pp. 1012-1024) https://doi.org/10.1016/j.carbon.2009.11.020
  57. Johansson and Campbell (2004) Reproducible XPS on biopolymers: cellulose studies (pp. 1018-1022) https://doi.org/10.1002/sia.1827
  58. Kameoka et al. (2019) Highly selective semi-hydrogenation of acetylene over porous gold with twin boundary defects (pp. 101-109) https://doi.org/10.1016/j.apcata.2018.10.027
  59. Liu et al. (2017) Synthesis and electronic properties of Ruddlesden-Popper strontium iridate epitaxial thin films stabilized by control of growth kinetics https://doi.org/10.1103/PhysRevMaterials.1.075004
  60. Zainab and Naz (2017) Daily living functioning, social engagement and wellness of older adults (pp. 93-102) https://doi.org/10.5964/pch.v6i1.213
  61. Eyasu et al. (2013) Photocatalytic degradation of methyl orange dye using Cr-doped ZnS nanoparticles under visible radiation (pp. 1452-1461)
  62. Indana et al. (2016) A novel green synthesis and characterization of silver nanoparticles using gum tragacanth and evaluation of their potential catalytic reduction activities with methylene blue and Congo red dyes (pp. 1-9) https://doi.org/10.1186/s40543-016-0098-1