10.1007/s40089-019-0270-x

Green chemistry synthesis of biocompatible ZnS quantum dots (QDs): their application as potential thin films and antibacterial agent

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  • Jejiron Maheswari Baruah1,
  • Sanjeeb Kalita2,
  • Jyoti Narayan*1,
  1. Synthetic Nanochemistry Laboratory, Department of Basic Sciences and Social Sciences (Chemistry Division), School of Technology, North Eastern Hill University, Shillong, 793022, IN
  2. Drug Discovery Lab, Biological and Chemical Sciences Section, Life Sciences Division, Institute of Advanced Study in Science and Technology (An Autonomous Institute Under Department of Science and Technology Government of India), Guwahati, Assam, 781035, IN
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Published in Issue 2019-03-27

How to Cite

Baruah, J. M., Kalita, S., & Narayan, J. (2019). Green chemistry synthesis of biocompatible ZnS quantum dots (QDs): their application as potential thin films and antibacterial agent. International Nano Letters, 9(2 (June 2019). https://doi.org/10.1007/s40089-019-0270-x
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Abstract

Abstract We are presenting here the synthesis of quantum dots (QDs) of direct band gap semiconductor, cubic ZnS through modified green chemistry-mediated chemical precipitation reaction. Green chemistry-synthesized (GCS) ZnS QDs were characterized using powder X-ray diffraction and high-resolution transmission electron microscope techniques. Analysis of results, revealed by both the techniques for the synthesized QDs, is complementary as far as the size range (2–6 nm) of ZnS QDs is concerned. UV–Vis spectrophotometric spectrum ( λ max  = 314 nm) showed a conspicuous blue shift than the bulk. The Fourier-transformed infrared spectra convincingly reported a Zn–S bond stretching frequency at 649 cm −1 . The characterized QDs were subjected to the preparation of thin films over SiO 2 template (57 nm thickness) using photoresist spin coating technique at the ambient condition. The surface topology of nanoscale-thick films was studied by atomic force microscope (roughness parameter—33.28 nm, rms; for a scan area of 3.48 × 3.48 μm 2 ). The symmetrical (skewness = 1.68) and random distribution (kurtosis = 2.93) of the peaks and valleys revealed the nanoscale-thick films of ZnS QDs. Zeta potential (− 9.2 mV) fairly proved stable existence of ZnS QDs. The GCS QDs were found to be non-toxic toward L929 mouse fibroblastic cells and human erythrocytes. However, they demonstrated significant inhibitory effects against seven bacterial pathogens with an average zone of inhibition of 1.5 cm at 100 μg/ml concentration. The minimum inhibitory concentrations determined were in the range of 75 to 125 μg/ml for gram-positive and 100 to 150 μg/ml for gram-negative bacterial pathogens.

Keywords

  • Zinc sulfide quantum dots,
  • Green synthesis,
  • Thin films,
  • Biocompatibility,
  • Antibacterial effect
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References

  1. Li et al. (2007) Synthesis and characterization of aqueous carboxyl-capped CdS quantum dots for bioapplications (pp. 2013-2019) https://doi.org/10.1021/ie060963s
  2. Jing et al. (2016) Aqueous based semiconductor nanocrystals (pp. 10623-10730) https://doi.org/10.1021/acs.chemrev.6b00041
  3. Dahl et al. (2007) Toward greener nanosynthesis (pp. 2228-2269) https://doi.org/10.1021/cr050943k
  4. Lu et al. (2017) A novel TiO2nanostructure as photoanode for highly efficient CdSe quantum dot-sensitized solar cells (pp. 9795-9802) https://doi.org/10.1039/c6ra26029b
  5. Wang et al. (2016) Mn doped quantum dot sensitized solar cells with power conversion efficiency exceeding 9% (pp. 877-886) https://doi.org/10.1039/c5ta09306f
  6. Nozik (2005) Exciton multiplication and relaxation dynamics in quantum dots: applications to ultrahigh-efficiency solar photon conversion (pp. 6893-6899) https://doi.org/10.1021/ic0508425
  7. Rühle et al. (2010) Quantum-dot-sensitized solar cells (pp. 2290-2304) https://doi.org/10.1002/cphc.201000069
  8. Salant et al. (2010) quantum dot sensitized solar cells with improved efficiency prepared using electrophoretic deposition (pp. 5962-5968) https://doi.org/10.1021/nn1018208
  9. Beard (2011) Multiple exciton generation in semiconductor quantum dots (pp. 1282-1288) https://doi.org/10.1021/jz200166y
  10. Hanna and Nozik (2006) Solar conversion efficiency of photovoltaic and photoelectrolysis cells with carrier multiplication absorbers https://doi.org/10.1063/1.2356795
  11. Semonin et al. (2011) Peak external photocurrent quantum efficiency exceeding 100% via MEG in a quantum dot solar cell (pp. 1530-1533) https://doi.org/10.1126/science.1209845
  12. Kamat et al. (2010) Beyond photovoltaics: semiconductor nanoarchitectures for liquid-junction solar cells (pp. 6664-6688) https://doi.org/10.1021/cr100243p
  13. Nozik (2002) Quantum dot solar cells (pp. 115-120) https://doi.org/10.1016/s1386-9477(02)00374-0
  14. Kamat (2013) Quantum dot solar cells. the next big thing in photovoltaics (pp. 908-918) https://doi.org/10.1021/jz400052e
  15. Yu et al. (2003) Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals (pp. 2854-2860) https://doi.org/10.1021/cm034081k
  16. Wang et al. (2016) Mn doped quantum dot sensitized solar cells with power conversion efficiency exceeding 9% (pp. 877-886) https://doi.org/10.1039/c5ta09306f
  17. Kershaw et al. (2017) Materials aspects of semiconductor nanocrystals for optoelectronic applications (pp. 155-205) https://doi.org/10.1039/c6mh00469e
  18. Kamat (2007) Meeting the clean energy demand: nanostructure architectures for solar energy conversion (pp. 2834-2860) https://doi.org/10.1021/jp066952u
  19. Michalet (2005) Quantum dots for live cells, in vivo imaging, and diagnostics (pp. 538-544) https://doi.org/10.1126/science.1104274
  20. Talapin et al. (2010) Prospects of colloidal nanocrystals for electronic and optoelectronic applications (pp. 389-458) https://doi.org/10.1021/cr900137k
  21. Kamat (1993) Photochemistry on nonreactive and reactive (semiconductor) surfaces (pp. 267-300) https://doi.org/10.1021/cr00017a013
  22. Thompson and Yates (2005) TiO2-based photocatalysis: surface defects, oxygen and charge transfer (pp. 197-210) https://doi.org/10.1007/s11244-005-3825-1
  23. Harris and Kamat (2009) Photocatalysis with cdse nanoparticles in confined media: mapping charge transfer events in the subpicosecond to second timescales (pp. 682-690) https://doi.org/10.1021/nn800848y
  24. Tachikawa et al. (2007) Mechanistic insight into the TiO2 photocatalytic reactions: design of new photocatalysts (pp. 5259-5275) https://doi.org/10.1021/jp069005u
  25. http://www.google.com/patents/US7916065
  26. . Accessed 29 Mar 2011
  27. NASA
  28. https://www.nasa.gov/feature/goddard/2017/nasa-and-mit-collaborate-to-develop-space-based-quantum-dot-spectrometer
  29. . Accessed 14 Feb 2017
  30. Wegner and Hildebrandt (2015) Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors (pp. 4792-4834) https://doi.org/10.1039/c4cs00532e
  31. Xing et al. (2007) Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry (pp. 1152-1165) https://doi.org/10.1038/nprot.2007.107
  32. Yezhelyev et al. (2007) In situ molecular profiling of breast cancer biomarkers with multicolor quantum dots (pp. 3146-3151) https://doi.org/10.1002/adma.200701983
  33. Smith et al. (2006) Multicolor quantum dots for molecular diagnostics of cancer (pp. 231-244) https://doi.org/10.1586/14737159.6.2.231
  34. Elward and Chakraborty (2013) Effect of dot size on exciton binding energy and electron-hole recombination probability in cdse quantum dots (pp. 4351-4359) https://doi.org/10.1021/ct400485s
  35. Franceschetti and Zunger (1997) Direct pseudopotential calculation of exciton coulomb and exchange energies in semiconductor quantum dots (pp. 915-918) https://doi.org/10.1103/physrevlett.78.915
  36. Kasap and Capper (2007) Springer https://doi.org/10.1007/978-0-387-29185-7
  37. Alivisatos (1996) Semiconductor clusters, nanocrystals, and quantum dots (pp. 933-937) https://doi.org/10.1126/science.271.5251.933
  38. Nozik et al. (2010) Semiconductor quantum dots and quantum dot arrays and applications of multiple exciton generation to third-generation photovoltaic solar cells (pp. 6873-6890) https://doi.org/10.1021/cr900289f
  39. Form EIA-63B, Annual Photovoltaic Module/Cell Manufacturers Survey, Energy Information Administration, USA, 2006
  40. Ginley et al. (2008) Solar Energy conversion toward 1 terawatt (pp. 355-364) https://doi.org/10.1557/mrs2008.71
  41. King et al. (2007) 40% efficient metamorphic GaInP∕GaInAs∕Ge multijunction solar cells https://doi.org/10.1063/1.2734507
  42. Dimroth and Kurtz (2007) High-efficiency multijunction solar cells (pp. 230-235) https://doi.org/10.1557/mrs2007.27
  43. Luque et al. (2007) Solar cells based on quantum dots: multiple exciton generation and intermediate bands (pp. 236-241) https://doi.org/10.1557/mrs2007.28
  44. Green (2006) Springer
  45. Martí (2004) Institute of Physics Publishing https://doi.org/10.1887/0750309059
  46. Kalita et al. (2017) Dual delivery of chloramphenicol and essential oil by poly-ε-caprolactone–Pluronic nanocapsules to treat MRSA-Candida co-infected chronic burn wounds (pp. 1749-1758) https://doi.org/10.1039/c6ra26561h
  47. Kandimalla et al. (2016) Fiber from ramie plant (Boehmeria nivea): a novel suture biomaterial (pp. 816-822) https://doi.org/10.1016/j.msec.2016.02.040
  48. Kotoky et al. (2015) Chloramphenicol encapsulated in poly-ε-caprolactone–pluronic composite: nanoparticles for treatment of MRSA-infected burn wounds https://doi.org/10.2147/ijn.s75023
  49. Kalita et al. (2016) Amoxicillin functionalized gold nanoparticles reverts MRSA resistance (pp. 720-727) https://doi.org/10.1016/j.msec.2015.12.078
  50. General Area Detector Diffraction System (GADDS) User Manual (2005). Bruker Advanced X-Ray Solutions.
  51. https://depts.washington.edu/moleng/wordpress/wp-content/uploads/2015/03/GADDS_Manual.pdf
  52. . Accessed Jan 2005
  53. Brunauer et al. (1938) Adsorption of gases in multimolecular layers (pp. 309-319) https://doi.org/10.1021/ja01269a023
  54. Murray et al. (1993) Synthesis and characterization of nearly monodisperse CdE (E = sulfur, selenium, tellurium) semiconductor nanocrystallites (pp. 8706-8715) https://doi.org/10.1021/ja00072a025
  55. Manzoor et al. (2009) Bio-conjugated luminescent quantum dots of doped ZnS: a cyto-friendly system for targeted cancer imaging https://doi.org/10.1088/0957-4484/20/6/065102
  56. Thomas (1999) Imperial College Press
  57. Kumar and Rao (2012) AFM Studies on surface morphology, topography and texture of nanostructured zinc aluminum oxide thin films (pp. 1881-1889)
  58. Chen et al. (2014) Single-step direct fabrication of luminescent Cu-doped ZnxCd1−xS quantum dot thin films via a molecular precursor solution approach and their application in luminescent, transparent, and conductive thin films (pp. 9640-9645) https://doi.org/10.1039/c4nr02237h
  59. Jayasree et al. (2011) Mannosylated chitosan-zinc sulphide nanocrystals as fluorescent bioprobes for targeted cancer imaging (pp. 37-43) https://doi.org/10.1016/j.carbpol.2011.01.034
  60. Chen et al. (2011) The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells https://doi.org/10.1088/0957-4484/22/10/105708
  61. Li et al. (2015) Blood compatibility evaluations of fluorescent carbon dots (pp. 19153-19162) https://doi.org/10.1021/acsami.5b04866
  62. Armentano et al. (2014) The interaction of bacteria with engineered nanostructured polymeric materials: a review (pp. 1-18) https://doi.org/10.1155/2014/410423
  63. Li et al. (2015) Enhancing the antimicrobial activity of natural extraction using the synthetic ultrasmall metal nanoparticles https://doi.org/10.1038/srep11033
  64. Luan et al. (2016) Complete wetting of graphene by biological lipids (pp. 5750-5754) https://doi.org/10.1039/C6NR00202A
  65. Gao et al. (2014) Nanoparticle approaches against bacterial infections (pp. 532-547) https://doi.org/10.1002/wnan.1282
  66. Mukha et al. (2013) Antimicrobial activity of stable silver nanoparticles of a certain size (pp. 199-206) https://doi.org/10.1134/S0003683813020117
  67. Xu et al. (2016) Exposure to TiO2 nanoparticles increases Staphylococcus aureus infection of HeLa cells https://doi.org/10.1186/s12951-016-0184-y
  68. Shrivastava et al. (2007) Characterization of enhanced antibacterial effects of novel silver nanoparticles https://doi.org/10.1088/0957-4484/18/22/225103
  69. Yang et al. (2009) Food storage material silver nanoparticles interfere with DNA replication fidelity and bind with DNA https://doi.org/10.1088/0957-4484/20/8/085102