10.1007/s40089-017-0207-1

Synthesis and characterisation of zinc oxide nanoparticles using terpenoid fractions of Andrographis paniculata leaves

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  • S. Kavitha*1,
  • M. Dhamodaran2,
  • Rajendra Prasad3,
  • M. Ganesan3,
  1. Department of Chemistry (R&DC), Bharathiar University, Coimbatore, Tamil Nadu, IN A.V.C. Polytechnic College, Nagai (DT), Tamil Nadu, 609305, IN
  2. Department of Chemistry (R&DC), Bharathiar University, Coimbatore, Tamil Nadu, IN Department of Chemistry, Perunthalaivar Kamarajar Institute of Engineering and Technology (PKIET) (Government of Puducherry Institution), Karaikal, Puducherry U.T., IN
  3. Department of Biochemistry and Biotechnology, Annamalai University, Chidambaram, Tamil Nadu, IN
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Published in Issue 2017-04-19

How to Cite

Kavitha, S., Dhamodaran, M., Prasad, R., & Ganesan, M. (2017). Synthesis and characterisation of zinc oxide nanoparticles using terpenoid fractions of Andrographis paniculata leaves. International Nano Letters, 7(2 (June 2017). https://doi.org/10.1007/s40089-017-0207-1
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Abstract

Abstract Zinc oxide (ZnO) nanoparticles have been widely employed for various pharmacological applications. Several approaches were tried to synthesize ZnO nanoparticles. In this study, ZnO nanoparticles were biosynthesized using terpenoid (TAP) fractions isolated from Andrographis paniculata leaves. Subsequently, the ZnNO 3 (0.1 N) is treated with the isolated TAP fractions to biosynthesize zinc oxide nanoparticles (Zn-TAP NPs). This nanoparticle preparation has been confirmed by the colour change from green to cloudy-white and the peak at 300 nm by UV–Visible spectra. FTIR analysis of Zn-TAP NPs showed the presence of functional group (i.e.) C=O which has further been confirmed by H 1 -NMR studies. From SEM and XRD analysis, it has been found that the hexagonal nanorod particle is 20.23 nm in size and +17.6 mV of zeta potential. Hence, it can be easily absorbed by negatively charged cellular membrane to contribute for efficient intracellular distribution. Therefore, it is suggested that the synthesised Zn-TAP NPs are more suitable in drug delivery processes.

Keywords

  • Terpenoids,
  • Nanoparticles,
  • Andrographis paniculata,
  • ZnNO3,
  • Zinc oxide nanoparticles
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