10.1007/s40089-022-00380-2

Copper nanoparticles and their oxides: optical, anticancer and antibacterial properties

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  • Muniratu Maliki1,
  • Ikhazuagbe H. Ifijen*2,
  • Esther U. Ikhuoria3,
  • Eribe M. Jonathan4,
  • Gregory E. Onaiwu4,
  • Ukeme D. Archibong5,
  • Augustine Ighodaro6,
  1. Department of Industrial Chemistry, Edo University Iyamho, Iyamho, Edo State, NG
  2. Department of Research Operations, Rubber Research Institute of Nigeria, Benin City, NG
  3. Department of Chemistry, University of Benin, Benin City, NG
  4. Department of Chemistry, Benson Idahosa University, Benin City, Edo State, NG
  5. Department of Science Laboratory Technology, University of Benin, Benin City, NG
  6. Quantum Pharmaceuticals, Durham, GB

Published in Issue 2022-09-17

How to Cite

Maliki, M., Ifijen, I. H., Ikhuoria, E. U., Jonathan, E. M., Onaiwu, G. E., Archibong, U. D., & Ighodaro, A. (2022). Copper nanoparticles and their oxides: optical, anticancer and antibacterial properties. International Nano Letters, 12(4 (December 2022). https://doi.org/10.1007/s40089-022-00380-2
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Abstract

Abstract The remarkable link between the strength and location of the Localized Surface Plasmon Resonance (LSPR) peak and the size, shape, and density of Cu NPs has been validated by numerous investigations on the optical properties of copper NPs. The prospect of attaining Cu NPs with tunable LSPR peak may be useful for developing catalysts, biosensors, optoelectronic devices, optical devices, etc .  The diversity, complexity and heterogeneity of cancer and bacteria-causing diseases have placed them among the most disheartening infections that threaten the health of humans for so many years. Investigations on copper oxide's optical, anticancer, and antibacterial properties have been carried out on a number of occasions due to their fascinating properties, which have been discovered as a potential therapeutic agent for the treatment of both cancer and bacteria-causing illnesses. Despite these established investigations, little review research has been done on the antibacterial and anticancer properties of copper NPs and their oxides. The optical properties of copper NPs and their oxides are not known to have any recorded review information. The optical characteristics of copper NPs and their efficacy in treating cancer and bacterial infections are highlighted in this review as a result. The mechanism of action of CuO NPson cancer strains and bacterial strains, challenges, and recommendations in the clinical application of copper nanomedicine were also highlighted. The evaluated studies developed copper oxide nanoparticles with enhanced optical characteristics; however, the methods and conditions used in each study's synthesis varied from study to study. Outstanding anticancer and antibacterial properties were exhibited by the studied copper oxide nanoparticles. It is clear that most approaches are still unable to bring copper nanosystems loaded with anticancer and antibacterial agents to the clinic; thus, additional work must be done to solve the major issues of the cancer epidemic and antibiotic resistance.

Keywords

  • Nanoparticles,
  • Copper oxide,
  • Anticancer,
  • Antibacterial

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