Microwave-assisted greener synthesis of Silver nanoparticles using Entada rheedii leaf extract and investigation of its anticancer and antimicrobial properties

Abstract

In the current investigation phytochemically mediated, easy, efficient, and eco-friendly green synthesis of silver nanoparticles (AgNPs) was carried out using Entada rheedii leaf extract as a reducing and capping agent in a microwave-assisted synthetic pathway. UV-Visible spectroscopy, IR spectroscopy, scanning electron microscope (SEM), and transmission electron microscopic (TEM) techniques were used to confirm the formation of silver nanoparticles. The functional groups present in the capping agent were identified by FTIR analysis.  SEM and TEM analysis studied the surface morphology of the biosynthesized AgNPs. AgNPs also showed significant antibacterial effects against four different bacterial pathogens Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Vibrio cholera. Additionally, the prepared AgNPs exhibited solid anticancer activity against Dalton's lymphoma ascites (DLA) cells.