Investigation of Skin Toxicity in Breast Cancer Patients Undergoing Radiation Therapy

Abstract

This study investigated skin toxicity in breast cancer patients undergoing radiation therapy. The study was conducted in 1401 at a radiation therapy center in Yazd city and included 30 patients who underwent radiation therapy using conventional and hypofractionation methods, and in which the whole or part of the breast was exposed to radiation. Skin complications of grade skin toxicity during treatment and within 40 days after radiotherapy were evaluated in both methods. Results showed that the four people (26.6%) had grade three and the six people (40.0%) had grade two skin toxicity, with conventional treatment causing more skin complications compared to hypofractionation, which caused fewer skin complications without reducing efficacy. Additionally, the ratio of skin complications in the conventional technique was higher than in the hypofractionation technique after 40 days of radiation therapy. The study concluded that hypofractionation results in fewer skin complications than conventional treatment.