OICC Press Trends in Phytochemical Research 2588-3631 1 3 2017 09 01 A new lupane triterpene glycoside from Euphorbia boissierana Prokh. 149 152 EN Lili Gvazava TSMU Iovel Kutateladze Institute of Pharmacochemistry, 36 P. Sarajishvili st., 0159 Tbilisi, Georgia Nana Gorgaslidze TSMU Iovel Kutateladze Institute of Pharmacochemistry, 36 P. Sarajishvili st., 0159 Tbilisi, Georgia Markus Ganzera Pharmacognosy, Institute of Pharmacy, University of Innsbruck, Innsbruck, Austria Alexander Skhirtladze TSMU Iovel Kutateladze Institute of Pharmacochemistry, 36 P. Sarajishvili st., 0159 Tbilisi, Georgia Journal Article 2017 09 01 Euphorbia plants displayed a wide range of biological activities including anticancer, antitumor, anti-diabetic, anticoagulant, antiproliferative, antioxidant, cytotoxic and modulation of multidrug resistance. Euphorbia boissierana Prokh. is one of the 45 species growing in Georgia. A new lupane triterpene glycoside (1) was isolated from the MeOH extract of the aerial parts of E. boissierana. The structure of 1 was elucidated as 3-[(O-β-D-fucopyranosyl-(12)-β-D-glucopyranosyl)oxy] lup-20(29)-en-3β, 28-diol. Structure elucidation was accomplished through the extensive use of 1D- and 2D NMR experiments including 1H–1H (COSY) and 1H–13C (HSQC, HMBC) spectroscopy along with ESI-MS and HR-ESI-MS.This is the first report of the isolation of betulin glycoside from the genus Euphorbia.