TY - EJOUR
AU - Khagoory, Rasha Kareem
AU - Abdullah, Siham Sabah
AU - Al-Shamae, Mohammed Sadoon
AU - Almilli, Zainab Hamid
PY - 2024
DA - July
TI - Iodine-131 planar sintigraphy compared to single photon emission computed tomography/computed tomography (SPECT/CT) imaging for the detection of thyroid cancer metastases in intermediate-risk and high-risk patients
T2 - Journal of Theoretical and Applied Physics
L1 - https://oiccpress.com/journal-of-theoretical-and-applied-physics/article/iodine-131-planar-sintigraphy-compared-to-single-photon-emission-computed-tomography-computed-tomography-spect-ct-imaging-for-the-detection-of-thyroid-cancer-metastases-in-intermediate-risk-and-high/
DO - 10.57647/j.jtap.2024.si-AICIS23.12
N2 - Traditional planar iodine-131 whole-body scan (WBS), which is frequently used to find radioiodine-avid metastases in thyroid cancer patients, is regarded as the standard diagnostic method. The constraints of planar iodine-131 whole-body scan in iodine-avid metastases have been addressed using SPECT/CT. The aim of this study was to compare iodine-131 SPECT/CT in the diagnosis of metastasis intermediate- and high-risk with thyroid carcinoma by radioactive iodine as therapy versus planar imaging. In a cross-sectional study, to sixty patients with diagnosed thyroid cancer 43 women and 17 men, ages 11 – 76 years to were examined at both the nuclear medicine sections of the Al-Andalus Private Hospital in Baghdad and the Al-Kawthar Nuclear Medicine Center in Basra. All patients had full or nearly full thyroid surgery. They received dose treatment with radioactive iodine-131 ranging from 3.7 GBq (100 mci) to 7.4 GBq (200 mci), after 5 days following the dosage, they had a planar whole body scan as well as SPECT/CT for the same day. Planar whole body scan and SPECT/CT data had been interpreted very differently for lymph node metastases and distant metastases, identifying sites of iodine uptake in some patients as it was judged equivocal, especially in the neck area, where the frequency of equivocal foci and middle cervical action was classified as a locoregional or thyroid residual illness. SPECT/CT interpreted the foci of iodine uptake sites thought to be equivocal detected on planar imaging. The results of the current study showed that the interpretation of uptake foci on whole-body planar imaging changed when the SPECT/CT results were reviewed, and the treatment plan had changed in 26 (43%) of 60 patients. This change was due to dependence on iodine uptake sites in the foci. The combination of SPECT/CT images had an increased greater than iodine-131 in planar scans in accurately defining central neck activity, and the incidence of radioactive avid metastases to lymphatic nodes (LN) on SPECT/CT was unusually large. SPECT/CT showed significantly more diagnostic data and additional benefit over whole-body planar scan for patients who received an oral therapeutic dose of iodine-131.
PB - OICC Press
KW - SPECT/CT, Whole-body planar scan, Thyroid carcinoma, Radioactive iodine 
EN -