Authors

• Ayad Khalaf Alhashimy ¹
• Abbas Abbd Latif * ²
• Abeer Qays Abdulwahab ¹
• Nihad Al-Hashimi ³

1. Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mustansiriyah, Baghdad, Iraq
2. Department of Clinical Laboratory Sciences, College of Pharmacy, University of Mustansiriyah, Baghdad, Iraq
3. School of Life Sciences, Pharmacy and Chemistry, Kingstone university, London, UK

Abstract

Considerable research has been carried out on diabetes mellitus (DM) and many materials have been used to treat the disease. Silver nanoparticles (AgNPs) have been used in many fields in medicine, and have been utilised in the treatment of DM in vivo successfully. In this paper, AgNPs were synthesized using a green
method and used with male albino mice (20 – 40) g. Light emitting diodes (LEDs) and lasers in the range (395 – 450) nm. AgNPs and LEDs or lasers were used in this work to evaluate their effect on diabetes mellitus.
It was found that AgNPs at the concentrations 6, 15, and 30 mg/kg reduced blood glucose level (BGL) to normal values. The best concentration that was found to treat DM is 15 mg/kg. However, at concentrations of 15 and 30 mg/kg, several deaths occured, but when laser or LED were used by radiating AgNPs, the deaths
decreased to a ratio of fifty percent. The laser and LED in the range of (395 – 450) nm made the drug active and reduced the deaths of animals to a ratio of 50%.

Keywords

• Laser
• Silver nanoparticles
• Alloxan
• Diabetes
• Mice
• Organic compounds
• Silver nitrate
• LED