OICC Press Journal of Nanostructure in Chemistry 2193-8865 6 3 (September 2016) 2016 06 24 Seagrass-mediated silver nanoparticles synthesis by Enhalus acoroides and its α-glucosidase inhibitory activity from the Gulf of Mannar 10.1007/s40097-016-0200-7 EN P. Senthilkumar PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN D. S. Ranjith Santhosh Kumar PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN B. Sudhagar PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN M. Vanthana PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN M. Hajistha Parveen PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN S. Sarathkumar PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN Jeslin Cheriyan Thomas PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN A. Sandhiya Mary PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN Chandramouleeswaran Kannan PG and Research Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamilnadu, 640 029, IN Journal Article 2016 06 24 Abstract Enhalus acoroides (Linnaeus f.) Royle belongs to the Family: Hydrocharitaceae is an abundantly growing seagrass in coastal areas of Gulf of Mannar. Sea grasses contain very good potent therapeutic properties for challenging diseases. The current investigation is to green synthesis Ag-NPs from Enhalus acoroides and characterize silver nanoparticles (Ag-NPs) and evaluated α-glucosidase inhibition activity. Furthermore, the characterization of the same using ultraviolet–visible spectroscopy (UV–Vis), Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), energy dispersive X-ray (EDX), and followed by Transmission Electron Microscopy (TEM). Surface Plasmon resonance exhibited the development of Ag-NPs in UV–Visible spectra at 419 nm. The FTIR examination was done to find and read the moiety accountable aimed at the bioconversion of silver ions. The crystalline form was observed in the XRD examination. The synthesized Ag-NPs were polydispersed spherical Ag-NPs as confirmed by EDAX and stabilized in the solution with the spherical shapes further confirmed by TEM analysis designate in the reading of 2–100 nm. The findings of the study shown that Ag-NPs of promisingly proved have strong α-glucosidase inhibitory activity by which Ag-NPs with an IC 50 47 µg/ml. This current research report is first to account on the green synthesis of silver nanoparticles from seagrass E. acoroides , because there is no literature survey and investigations on Enhalus acoroides . Hence, we suggest that Ag-NPs synthesized from E. acoroides might be a significant resource of α-glucosidase inhibitors preparation that may benefit diabetes treatment.