OICC Press Journal of Nanostructure in Chemistry 2193-8865 5 1 (March 2015) 2014 10 07 Facile microwave-assisted synthesis of 2-aryloxazolo[4,5-b]pyridines using SBA-Pr-NH2 10.1007/s40097-014-0129-7 EN Ghodsi Mohammadi Ziarani Department of Chemistry, Alzahra University, Tehran, IR Monireh Shakiba Nahad Department of Chemistry, Alzahra University, Tehran, IR Negar Lashgari School of Chemistry, College of Science, University of Tehran, Tehran, IR Alireza Badiei School of Chemistry, College of Science, University of Tehran, Tehran, IR Journal Article 2014 10 07 Abstract Abstract In this work, amino-functionalized SBA-15 (SBA-Pr-NH 2 ) has been used as a basic nano-catalyst in the one-pot synthesis of 2-aryloxazolo[4,5- b ]pyridines by the condensation reaction of 2-amino-3-hydroxypyridine and benzoyl chlorides under microwave irradiation in solvent free conditions. Among the advantages of this work are short reaction times, high yields and simple work-up. SBA-Pr-NH 2 as an efficient heterogeneous nanoporous solid basic catalyst which was prepared by silica functionalization with 3-aminopropyltriethoxysilane, can be easily removed from the reaction mixture by simple filtration, and also recovered and reused without noticeable loss of reactivity. 2-Aryloxazolo[4,5- b ]pyridines have different pharmacological activities (anti-inflammatory, anti-pyretic, analgesic, antifungal). In the current method for the synthesis of 2-aryloxazolo[4,5- b ]pyridines, no hazardous organic solvent was used and simplicity of the procedure provides significant improvements over many of other existing methods. Furthermore, the SBA-15-Pr-NH 2 with pore size of 6 nm can act as nano-reactor. Graphical Abstract