TY - EJOUR
AU - Safaei-Ghomi, Javad
AU - Shahbazi-Alavi, Hossein
PY - 2024
DA - February
TI - Synthesis of dihydrofurans using biosynthesized CuO nanoparticles
T2 - Iranian Journal of Catalysis
VL - 8
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/synthesis-of-dihydrofurans-using-biosynthesized-cuo-nanoparticles/
N2 - The preparation of trans-dihydrofurans has been achieved by a one-pot condensation reaction of 4-bromophenacyl bromide, aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione using biosynthesized CuO nanoparticles under reflux conditions in ethanol. CuO nanoparticles (CuO NPs) were prepared using extractof leaves of Ajuga chamaecistus Subsp. Scoparia. The key advantages of this process are the diastereoselective synthesis, reusability of the catalyst, low catalyst loading, excellent yields, short reaction times, simple workup and environmentally benign. Fully optimized structures of trans and cis dihydrofurans were obtained by B3LYP/6-31G(d,p) method. The structures of the prepared trans-2,3-dihydrofurans were fully characterized by 1H and 13C NMR spectra, IR spectra, and elemental analysis.
IS - 4
PB - OICC Press
KW - Dihydrofurans, Biosynthesized CuO nanoparticles, One-pot, Green synthesis, Reusable catalyst. 
EN -