TY - EJOUR
AU - Salehi, Naeimeh
AU - Mirjalili, Bi Bi Fatemeh
PY - 2024
DA - February
TI - Biomimetic synthesis of 1-aryl-2,5-dimethyl pyrroles using egg white nano-ovalbumin at room temperature under solvent-free conditions
T2 - Iranian Journal of Catalysis
VL - 9
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/biomimetic-synthesis-of-1-aryl-25-dimethyl-pyrroles-using-egg-white-nano-ovalbumin-at-room-temperature-under-solvent-free-conditions/
N2 - Ovalbumin, as the major component of egg-white, is a globular, biocompatible, nontoxic and biodegradable phosphoglyco protein. This protein with the molecular weight of 44.5 kDa, contains 385 residues of amino acids with isoelectric point (pI) of 4.5. Many purification procedures have been reported for egg-white proteins such as gel permeation and anion exchange chromatography. In this study, we have reported a new inexpensive protocol using acetic acid and sodium chloride for extraction and purification of egg white nano-ovalbumin. The effective performance of this protein as a biocatalyst was proved through synthesis of N-substituted pyrrole derivatives. This reported innovative biomethodology has some advantages such as less pollution, mild reaction conditions, reusability of biocatalyst and excellent yields.
IS - 3
PB - OICC Press
KW - N-substituted pyrroles, Egg white nano-ovalbumin, Biocatalyst, Paal-Knorr reaction 
EN -