TY - EJOUR
AU - Bazgir, Ayoob
AU - Azimi, Seyyedeh Cobra
PY - 2024
DA - February
TI - Facile one-pot synthesis of pyrimido[4,5-d]pyrimidine-2,4-diones in Ionic Liquid and study of their antibacterial activities
T2 - Iranian Journal of Catalysis
VL - 3
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/facile-one-pot-synthesis-of-pyrimido45-dpyrimidine-24-diones-in-ionic-liquid-and-study-of-their-antibacterial-activities/
N2 - A simple, novel, efficient and three-component procedure for the synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives by the reaction of 6-amino-1,3-dimethyluracil, aldehyde and 2-benzylisothiourea hydrochloride promoted by ionic liquid 1-butyl-3-methylimidazolium bromide ([BMIm]Br) under solvent-free conditions is reported. The presented method is benefited from operational simplicity, simple workup and reusability of ionic liquid. These products were evaluated in vitro for their antibacterial activities.
IS - 1
PB - OICC Press
KW - Ionic liquid, Pyrimido[4, 4-dione, 5-d]pyrimidine-2, 6-Amino-uracil, Antibacterial activities 
EN -