TY - EJOUR
AU - Youseftabar-Miri, Leila
AU - Rafieirad, Maryam
PY - 2024
DA - February
TI - Tetramethylguanidiniumtriflate catalyzed Henry reaction of isatins: An efficient synthesis of 3-hydroxy-3-(nitromethyl)indolin-2-one derivatives and their anti-diabetic activity
T2 - Iranian Journal of Catalysis
VL - 5
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/tetramethylguanidiniumtriflate-catalyzed-henry-reaction-of-isatins-an-efficient-synthesis-of-3-hydroxy-3-nitromethylindolin-2-one-derivatives-and-their-anti-diabetic-activity/
N2 - The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity.(The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity, i try to submit paper)
IS - 1
PB - OICC Press
KW - Henry reaction, Oxindole, Ionic liquid, Isatin 
EN -