TY - EJOUR
AU - Khandan-Barani, Khatereh
AU - Motamedi-Asl, Arezo
PY - 2024
DA - February
TI - Lactic acid, as an efficient catalyst for the one-pot three-component synthesis of 1-amidoalkyl-2-naphthols under thermal solvent-free conditions
T2 - Iranian Journal of Catalysis
VL - 5
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/lactic-acid-as-an-efficient-catalyst-for-the-one-pot-three-component-synthesis-of-1-amidoalkyl-2-naphthols-under-thermal-solvent-free-conditions/
N2 - For the first time lactic acid was applied as an efficient and green catalyst for the one-pot three-component synthesis of amidoalkyl naphthols via the condensation between arylaldehydes, 2-naphthol and amides or urea under thermal solvent-free conditions in good to excellent yields. We have demonestrated a mild and efficient eco-friendly tandem synthesis of amidoalkyl naphthols using lactic acid as a novel organoacid green promoter, which uses neither harsh conditions nor the use of hazardous or toxicant catalysts and reagents. This methodology has a number of advantages including: short reaction times, high yield, use of non-toxic and inexpensive catalyst, elimination of solvent and easy work-up.
IS - 4
PB - OICC Press
KW - Solvent-free, Lactic acid, Amidoalkyl naphthol, Thermal condition 
EN -