TY - EJOUR AU - Kheilkordi, Zohreh AU - Ziarani, Ghodsi Mohammadi AU - Gholamzadeh, Parisa AU - Badiei, Alireza PY - 2024 DA - February TI - Application of SBA-Pr-SO3H as a solid acid nanoreactor in the Biginelli reaction T2 - Iranian Journal of Catalysis VL - 6 L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/application-of-sba-pr-so3h-as-a-solid-acid-nanoreactor-in-the-biginelli-reaction/ N2 - Sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) with a pore size of 6 nm catalyzed three component coupling of aromatic aldehydes, urea and ethyl acetoacetate to afford the corresponding dihydropyrimidinones under solvent free condition. This new protocol for Biginelli reaction has important advantages such as green synthesis, short reaction time, easy isolation and high yields of products and reusability of the catalyst. SBA-Pr-SO3H was proved to be an efficient heterogeneous nanoporous solid acid catalyst which could be easily handled and removed from the reaction mixture by simple filtration and can be recovered and reused for several times without any loss of activity. IS - 3 PB - OICC Press KW - Green synthesis, Biginelli reaction, Dihydropyrimidinone, SBA-Pr-SO3H EN -