TY - EJOUR AU - Kheilkordi, Zohreh AU - Ziarani, Ghodsi Mohammadi AU - Rahimifard, Mahshid AU - Hajiashrafi, Taraneh AU - Badiei, Alireza AU - Soorki, Ali Abolhassani PY - 2024 DA - February TI - One-pot synthesis of tetrahydropyrimido[4,5-b]quinoline derivatives using sulfonic acid functionalized SBA-15 and their antimicrobial activities T2 - Iranian Journal of Catalysis VL - 7 L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/one-pot-synthesis-of-tetrahydropyrimido45-bquinoline-derivatives-using-sulfonic-acid-functionalized-sba-15-and-their-antimicrobial-activities/ N2 - A Simple and efficient method for synthesis of tetrahydropyrimido[4,5-b]quinoline derivatives via three component reaction of aromatic aldehydes, dimedone and 6-amino uracil derivatives using a catalytic amount of sulfonic acid functionalized nanoporous silica (SBA-15-Pr-SO3H) is described. The advantages of this method are easy and clean work-up, high yield, mild reaction condition, reusable catalyst and environmentally benign solvents. Antibacterial and antifungal activities of synthesized compounds were measured against gram positive, gram negative bacteriaand fungus. Only compounds 4c and 4g showed activity against Staphylococcus aureus. IS - 1 PB - OICC Press KW - Multi-component reaction, Dimedone, Aldehydes, 4(6)-Amino uracil, SBA-15-Pr-SO3H EN -