TY - EJOUR
AU - Shrivas, Prabhakar
AU - Punyapreddiwar, Nitesh
AU - Wankhade, Atul
AU - Zodape, Sangesh
AU - Pratap, Umesh
PY - 2024
DA - February
TI - Baker’s yeast catalyzed Henry reaction: Biocatalytic C-C bond formation
T2 - Iranian Journal of Catalysis
VL - 7
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/bakers-yeast-catalyzed-henry-reaction-biocatalytic-c-c-bond-formation/
N2 - The C-C bond formation is an important reaction in organic synthesis to obtain value-added intermediates. Therefore, in this paper an attempt has been made to accelerate the Henry reaction (C-C bond formation) between aryl aldehydes and nitromethane using less expensive whole cell biocatalyst, baker’s yeast (BY). The scope of the methodology was also tested for the heteryl aldehyde i.e. 2-chloro-3-formyl quinoline to obtain the corresponding quinoline containing nitroalcohol. The developed protocol is highly efficient and completely environmentally friendly. The work addressed the issue of non-aqueous biocatalysis, since Henry reaction catalysed by baker’s yeast has been carried out in ethanol.
IS - 4
PB - OICC Press
KW - β-Nitroalcohol, Baker’s yeast, Biocatalysis, Henry reaction 
EN -