TY - EJOUR
AU - Shaikh, Mohd Akmal
AU - Farooqui, Mazahar
AU - Abed, Syed
PY - 2024
DA - February
TI - Morpholinium glycolate as an efficient and reusable catalyst for the synthesis of bis(pyrazol-5-ol) derivatives under solvent-free conditions
T2 - Iranian Journal of Catalysis
VL - 8
L1 - https://oiccpress.com/iranian-journal-of-catalysis/article/morpholinium-glycolate-as-an-efficient-and-reusable-catalyst-for-the-synthesis-of-bispyrazol-5-ol-derivatives-under-solvent-free-conditions/
N2 - In this paper, an environmentally benign access to synthesize Bis(pyrazol-5-ol) derivatives was developed through the one pot pseudo five component condensation reaction of phenyl hydrazine with ethyl acetoacetate, and different aryl/heteroaryl aldehydes using morpholinium glycolate as the homogeneous reusable catalyst under solvent-free conditions at 80 °C. Further, the ionic liquid was prepared and characterized by FT-IR, 1HNMR, 13CNMR and TG-DTG techniques. The present synthetic protocol offers excellent yields of the products, short reaction times, clean and simple work up, reusability of catalyst up to five runs, a significant reduction in cost, and eco-efficient alternative to the existing methods.
IS - 2
PB - OICC Press
KW - Ionic Liquids, Bis(pyrazol-5-ol)s, Morpholinium glycolate, Homogeneous catalyst 
EN -