@article{Mokhtary_2024, title={Green approach for the synthesis of pyranopyrazoles and hexahydroquinoline-3-carboxamides using unripe grape juice (verjuice) as catalyst}, volume={9}, url={https://oiccpress.com/iranian-journal-of-catalysis/article/green-approach-for-the-synthesis-of-pyranopyrazoles-and-hexahydroquinoline-3-carboxamides-using-unripe-grape-juice-verjuice-as-catalyst/}, abstractNote={Unripe grape juice (verjuice) as a natural catalyst was successfully applied to perform the one-pot reaction of aryl aldehydes, malononitrile, hydrazine hydrate and ethyl acetoacetate to synthesize pyranopyrazole derivatives in aqueous ethanol at room temperature in excellent yields. Furthermore, unripe grape juice catalyzed one-pot synthesis of hexahydroquinoline-3-carboxamide derivatives by the four-component reaction of arylaldehydes, dimedone, acetoacetanilide and ammonium acetate in high to excellent yield in ethanol at 70 ℃. The synthesized compounds were identified by FT-IR, 1H NMR and 13C NMR spectroscopic techniques and elemental analysis. An environmentally benign procedure, short reaction time, high yields and biocompatible natural catalyst are some advantages of this research.}, number={1}, journal={Iranian Journal of Catalysis}, publisher={OICC Press}, author={Mokhtary, Masoud}, year={2024}, month={Feb.}, keywords={Pyranopyrazoles, Unripe grape juice, Hexahydroquinoline-3-carboxamides, Multi-component reactions} }