@article{Aboonajmi_Maghsoodlou_Hazeri_Lashkari_Safarzaei_Shirzaei_2024, title={Multicomponent preparation of highly functionalized piperidines using FeCl3.6H2O as an efficient catalyst}, volume={5}, url={https://oiccpress.com/iranian-journal-of-catalysis/article/multicomponent-preparation-of-highly-functionalized-piperidines-using-fecl3-6h2o-as-an-efficient-catalyst/}, abstractNote={FeCl3.6H2O was used as an efficient catalyst for the synthesis of highly functionalized piperidines via a one-pot five-component reaction of aromatic amines, aromatic aldehydes and β-keto esters in EtOH at room temperature. The remarkable advantages offered by this method are good yields, simple procedure, short reaction times, no need to column chromatography and easy work-up. The structures of all compounds were characterized by comparison of their IR and NMR spectra with authentic samples. Also, the relative stereochemistry of these piperidines has been confirmed by single X-ray crystallography analysis in previously reported literature. Starting materials with electron-deficient or electron-releasing groups were reacted efficiently.}, number={1}, journal={Iranian Journal of Catalysis}, publisher={OICC Press}, author={Aboonajmi, Jasem and Maghsoodlou, Malek Taher and Hazeri, Nourallah and Lashkari, Mojtaba and Safarzaei, Mohyeddin and Shirzaei, Moheb}, year={2024}, month={Feb.}, keywords={Aldehyde, Multicomponent, Functionalized piperidine, β-Keto ester} }