@article{Youseftabar-Miri_Rafieirad_2024, title={Tetramethylguanidiniumtriflate catalyzed Henry reaction of isatins: An efficient synthesis of 3-hydroxy-3-(nitromethyl)indolin-2-one derivatives and their anti-diabetic activity}, volume={5}, url={https://oiccpress.com/iranian-journal-of-catalysis/article/tetramethylguanidiniumtriflate-catalyzed-henry-reaction-of-isatins-an-efficient-synthesis-of-3-hydroxy-3-nitromethylindolin-2-one-derivatives-and-their-anti-diabetic-activity/}, abstractNote={The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity.(The ionic liquid, N,N,N,N-tetramethylguanidiniumtriflate (TMGTf) was found to be an efficient catalyst solvent for Henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. The ionic liquid amenable to successive recycling without appreciable decrease in activity. Synthesized compounds have been screened for their anti-diabetic activity, i try to submit paper)}, number={1}, journal={Iranian Journal of Catalysis}, publisher={OICC Press}, author={Youseftabar-Miri, Leila and Rafieirad, Maryam}, year={2024}, month={Feb.}, keywords={Henry reaction, Oxindole, Ionic liquid, Isatin} }