@article{Pour_Maghsoodlou_Heydari_Lashkari_2024, title={Oxalic acid dihydrate catalyzed synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives under thermal and solvent-free conditions}, volume={6}, url={https://oiccpress.com/iranian-journal-of-catalysis/article/oxalic-acid-dihydrate-catalyzed-synthesis-of-34-dihydropyrimidin-2-1h-one-derivatives-under-thermal-and-solvent-free-conditions/}, abstractNote={Oxalic acid dihydrate as a green, mild and efficient catalyst for the one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives from the reaction between β-keto esters (methyl or ethyl acetoacetate), aromatic aldehyde (benzaldehye derivatives) and urea or thiourea under thermal and solvent-free conditions with excellent yields and short reaction time is studied. The most remarkable benefits of this synthetic method include the green methodology, an eco-friendly, inexpensive and non-toxic catalyst, solvent-free conditions, the availability of materials, and a simple operational procedure with no column chromatographic separation. The products were characterized by melting points, IR and 1H NMR spectroscopy.}, number={2}, journal={Iranian Journal of Catalysis}, publisher={OICC Press}, author={Pour, Farzaneh Mohamad and Maghsoodlou, Malek Taher and Heydari, Reza and Lashkari, Mojtaba}, year={2024}, month={Feb.}, keywords={Green methodology, 4-Dihydropyrimidinone., Biginelli reaction, Oxalic acid.2H2O} }