@article{Bakherad_Keivanloo_Amin_Ghmari_2024, title={Silica-anchored Cu(I) aminothiophenol complex: An efficient heterogeneous catalyst for synthesis of 1,4-disubstituted 1,2,3-triazoles in water}, volume={8}, url={https://oiccpress.com/iranian-journal-of-catalysis/article/silica-anchored-cui-aminothiophenol-complex-an-efficient-heterogeneous-catalyst-for-synthesis-of-14-disubstituted-123-triazoles-in-water/}, abstractNote={An efficient method has been developed for synthesis of 1,4-disubstituted 1,2,3-triazoles using the silica-anchored Cu(I) aminothiophenol complex [SiO2-AT-Cu(I)] as a novel heterogeneous catalyst. The prepared catalyst is characterized by the FT-IR spectroscopy, and TGA, SEM, and ICP techniques. Terminal alkynes react with aroyl bromides and sodium azide in the presence of CuI anchored on silica in water at 80°C. The reactions exclusively generate the corresponding regiospecific 1,4-disubstituted 1,2,3-triazoles in good yields. The attractive features of this method are the simple procedure, clean reaction, use of a reusable catalyst, easy workup, and performing a click reaction in water. Moreover, the catalyst can be removed from the reaction mixture by means of simple filtration, and used again for up to five runs without a remarkable loss in its activity.}, number={3}, journal={Iranian Journal of Catalysis}, publisher={OICC Press}, author={Bakherad, Mohammad and Keivanloo, Ali and Amin, Amir Hossein and Ghmari, Pooya}, year={2024}, month={Feb.}, keywords={Click reaction, 3-triazole, Aroyl bromide, Silica-supported} }