Nanotechnology has slowly but steadily revolutionized the diagnosis, imaging and treatment of cancer. Detecting cancer at earliest stages, locating the tumor at different areas in the body and specific delivery of the drugs to malignant cells including surgically inaccessible tumors are the core areas of medical and pharmaceutical research across the world. In this endeavour, […]
Giant Unilamellar Vesicles (GUVs) consisting in self-closed lipid bilayers of 0.5-100 µm diameter are considered as oversimplified models of cells because of their biological membrane and micrometric size while Large Unilamellar Vesicles (LUVs) of 100-500 nm diameter have applications in drug delivery. To improve structural and mechanical properties of these vesicles, we have developed two […]
Nowadays nanotechnology as a new direction of science allows us to develop therapeutic methods of the endogenous intoxication syndrome and to create a new class of biocompatible sorbents. In Ukraine first preparations of medical nanotechnology were produced and patented in 1998. These are IKBB (intracorporeal biocorrector), magnet-controlled sorbent (MCS-B), and Micromage-B. The preparations are based […]
In this paper we report an eco-friendly route for the synthesis of sliver nanoparticles using Agaricus bisporus (white button mushroom) extract. The synthesized silver nanoparticles were confirmed and characterized by UV-Visible spectrum of the aqueous solution containing silver ions showed a peak at 420 nm corresponding to the surface plasmon absorbance of silver nanoparticles. Transmission […]
Interpenetrating polymer networks (IPN) were formed involving hydrophobic polybutyl acrylate (PBA) and hydrophilic poly hydroxyethyl acrylate (PHEA). PBA prepolymer was first formed in presence of ferric oxide nanoparticles (
The efficient detection of charged biomolecules by biosensor with appropriate semiconducting nanomaterials and with optimum device geometry has caught tremendous research interest in the present decade. Here, the performance of various label-free electronic biosensors to detect bio-molecules is investigated by simulation technique. Silicon nanowire sensor, nanosphere sensor and double gate field effect transistor (DGFET) sensor […]
Large unilamellar liposomes and multilamellar vesicles consisting of DMPC interacted with cationic phosphorus-containing dendrimers CPDs G3 and G4. DSC and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. Calorimetric studies indicate that the enthalpy of the transition of the lipids that interact with CPDs […]
We report the direct soft chemical synthesis and characterization of a family of face centered cubic (fcc) and partially ordered face centered tetragonal (fct) FePt nanoparticles (NPs) suitable for biomedical applications. Both fcc and partially ordered fct-FePt NPs are synthesized by employing a simple polyol method. By using polyvinyl pyrolidone (PVP) as a stabilizer in […]
Patient noncompliance to current tuberculosis (TB) therapy owing to multidrug administration daily leads to treatment failure and emergence of multidrug resistant and extensively drug resistant TB. To avoid the daily dosing, application of nanotechnology is the only viable solution by virtue of sustained release of drugs. Other potential advantages of the system include the possibility […]
