TY - EJOUR AU - Zebari, Khalid Mohammed Sharif AU - AL-Mezory, Abdullkareem Ramazan AU - Faizy, Hadar Saaeed PY - 2024 DA - February TI - Antibacterial effect of bioceramic root canal sealer (BioRootTM) modified with Thymus Kotschyanus Boiss T2 - International Journal of Industrial Chemistry VL - 14 L1 - https://oiccpress.com/international-journal-of-industrial-chemistry/article/antibacterial-effect-of-bioceramic-root-canal-sealer-bioroottm-modified-with-thymus-kotschyanus-boiss/ DO - 10.57647/j.ijic.2023.1402.08 N2 - The present study aimed to evaluate the antibacterial efficacy of bioceramic root canal sealer modified with herbal extracts, because there are insufficient scientific reports that indicate the antibacterial effects of herbal extracts added to endodontic root canal sealers. The essential oils of the aerial parts of Thymus Kotschyanus Boiss were obtained by hydrodistillation (HD) method and analyzed by Gas Chromatography-Mass Spectrometry (GC/MS) Analysis, and the major compounds were carvacrol (53.61) and thymol (12.78). The herbal extracts were added in different percentages to BioRootTM root canal sealer to know the effective concentration against the E. faecalis bacteria by placing into the agar base, and the zones of inhibitions were measured. The groups were assessed as AH Plus (control), BioRootTM, and (BioRootTM+Thymus Kotschyanus Boiss) Exp. Material (1-4)%, Exp. Material (1-2)%, Exp. Material (1-1)% and for evaluating the antibacterial activity the agar diffusion test (ADT) was used. The AH Plus (control) exhibited the largest inhibition zone 10.05 (0.99) mm, followed by Exp. Material (1-1)% 7.82(0.77) mm, Exp. Material (1-2)% 4.96 (0.60) mm, while the least inhibition zone was found in BioRootTM 4.39 (0.55) mm and Exp. Material (1-4)% was 4.36 (0.59) mm. Using ANOVA one-way test, there was a statistically significant difference of inhibition zone among root canal sealers. Based on results, statistical analysis and observation of the AH Plus sealer and Exp. Material (1-1)% had higher antibacterial effects than BioRootTM sealer, so the oil of Thymus Kotschyanus Boiss can be added as one of the components of root canal sealer, but farther research is needed before recommending it as sealers. IS - 2 PB - OICC Press KW - Thymus Kotschyanus Boiss, BioRoot TM, AH Plus, Agar diffusion test, E. faecalis, Antibacterial activity EN -