OICC Press International Nano Letters 2228-5326 11 3 (September 2021) 2021 05 18 Potentials of phytosynthesized silver nanoparticles in biomedical fields: a review 10.1007/s40089-021-00341-1 EN Sunday Adewale Akintelu MOE Key Laboratory of Cluster Science, Beijing Key Laboratory of Photoelectronic Electrophotonic Conversion Materials, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102488, CN Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, NG Seyifunmi Charles Olugbeko Department of Agricultural Economics, Ladoke Akintola University of Technology, Ogbomoso, NG Aderonke Similoluwa Folorunso Department of Chemistry, Louisiana State University, Louisiana, US Abel Kolawole Oyebamiji Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, NG Department of Basic Sciences, Adeleke University, Ede, Osun State, NG Femi Adekunle Folorunso Department of Anatomy, Osun State University, Osogbo, NG Journal Article 2021 05 18 Abstract Nanoscience and nanotechnology are currently undergoing several developments that will impact several industries across the global in due season. The wide applications of nanoparticles in biomedicine, pharmacy, phytochemistry, research institute, catalysis, textile, waste water management, chemistry, food preservatives, and paint have led to new area of discoveries for many researchers and industries. The biological method of synthesizing silver nanoparticles (AgNPs) had tremendously gained wide popularity due to its environmental friendly conditions of synthesis. Numerous biological entities namely; plants, bacteria, essential oil, fungi, algae, and yeasts had been used as reducing and capping agent for the synthesis of AgNPs. All scientific investigations have ascertained the uniqueness of AgNPs as therapeutic agent against cancer, virus, bacterial, and fungal infections. This review provides detailed scientific information about the various methods of synthesis, optimization conditions, mechanism, and characterization techniques for the synthesis of AgNPs with efficient yield and morphological properties. Furthermore, concise advancement in the antibacterial, antiviral, antifungal, antioxidant, and anticancer activities of AgNPs mediated from plant sources from recently published articles were enumerated.