OICC Press International Journal of Nano Dimension 2228-5059 16 2 2025 04 01 Synthesis of new ethyl cyanoacetate analogs catalyzed by nano-Fe3O4@EA 10.57647/j.ijnd.2025.1602.11 EN Tahereh Moradhosseini Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran https://orcid.org/0009-0006-3898-8247 Masoud Mokhtary Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran https://orcid.org/0000-0003-3763-7139 Mohammad Nikpassand Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran https://orcid.org/0000-0002-9692-6849 Majid Kia Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran https://orcid.org/0000-0001-8945-8496 Leila Asadpour Department of Microbiology, Rasht Branch, Islamic Azad University, Rasht, Iran https://orcid.org/0000-0002-8437-0337 Journal Article 2025 04 01 In this research, we present an effective method for synthesizing new derivatives of ethyl cyanoacetate through base-free Knoevenagel condensation using ellagic acid-bonded magnetic nanoparticles (nano-Fe3O4@EA) as a catalyst. This method offers several advantages, including high yield, short reaction time, and simplicity, making it an attractive and efficient option in the emerging field of Knoevenagel condensation.