OICC Press International Journal of Mathematical Modelling & Computations 2228-6233 10 3 2020 09 01 A ‎M‎odel of Coronavirus Pandemic Spread with Lockdown and Quarantine 161 177 EN Dejen Mamo Department of Mathematics, College of Natural and Computational Sciences, Debre Berhan University, Debre Berhan, Ethiopia. Journal Article 2020 09 01 In this work, a researcher develop $SHEIQRD$ (Susceptible-Stay at home-Exposed-Infected-Quarantine-Recovery-Death) coronavirus pandemic spread model. The disease-free and endemic equilibrium points are calculated and analyzed. The basic reproductive number $R_0$ is derived and its sensitivity analysis is done. COVID-19 pandemic spread is die out when $R_0leq 1$ and its persist in the community whenever $R_0>1$. More than $10%$ of lockdown or home quarantine, above $50%$ and $30%$ identification and isolation of expose and infected individuals respectively, and reduction home quarantine return rate(less than $10%$) can be mitigates the pandemics. Finally, theoretical analysis and numerical results are consistent.