OICC Press International Journal of Energy and Environmental Engineering 2251-6832 17 01 2026 03 31 Optimization of Energy Consumption in Office Buildings: A Sustainable Design and Novel Materials Approach 10.57647/ijeee.2026.1701.06 EN Hedieh Dabiri Department of Architecture, ST.C, Islamic Azad University, Tehran, Iran Rasool Pahlavanpour Department of Architecture, ST.C, Islamic Azad University, Tehran, Iran https://orcid.org/0000-0002-2836-2746 Journal Article 2026 03 31 Optimizing energy performance and achieving sustainable design in buildings are critical global challenges. This study addresses these challenges by examining the Molla Sadra Administrative-Educational Building as a case study for data‑driven sustainable design. Using a mixed‑methods approach, the research integrates theoretical analysis, energy simulation, life cycle assessment (LCA), and machine learning (ML) applied to twelve months of operational data. Advanced models, including Random Forest and MLP, achieved an accuracy of 92% in predicting energy consumption and identified three primary influencing factors: occupancy (38%), solar radiation (24%), and ventilation (19%). Based on these insights, dynamic temperature adjustments between 22 °C and 25 °C were recommended, leading to an estimated 18% reduction in energy use. The discussion highlights the synergy between sustainable architectural design and intelligent data utilization in enhancing building performance. Overall, the Molla Sadra project is positioned as a benchmark for sustainable, data‑driven buildings that achieve substantial reductions in both energy consumption and carbon emissions.