OICC Press Iranian Journal of Catalysis 2345-4865 14 4 2024 11 16 Fabrication of a New Magnetic Nanocatalyst and its Application for the Effectual Construction of Pyrimido[4,5-b]Quinolines 1 11 10.57647/j.ijc.2024.1404.43 EN Abdolkarim Zare Department of Chemistry, Faculty of Nano and Bio Science and Technology, Persian Gulf University, Bushehr, Iran https://orcid.org/0000-0002-8210-3155 Marziyeh Barzegar Department of Chemistry, Payame Noor University, Tehran, Iran Ahmad Reza Moosavi-Zare Department of Chemical Engineering, Hamedan University of Technology, Hamedan, Iran AND Chemistry Department, College of Sciences, Shiraz University, Shiraz, Iran https://orcid.org/0000-0003-0321-9326 Journal Article 2024 11 16 A new magnetic nanocatalyst, namely [Fe3O4@SiO2@RNMe2-SO3H][CF3CO2] (FSRNSC), was fabricated, and characterized using FT-IR, EDS (energy-dispersive X-ray spectroscopy), elemental mapping, FE-SEM (field-emission scanning electron microscopy), XRD (X-ray diffraction), VSM (vibrating-sample magnetometry), TG (thermogravimetric) and DTG (differential thermogravimetric) analyses. It was utilized as a highly effectual and magnetically recoverable catalyst for the construction of pyrimido[4,5-b]quinolines (12 examples) in high yields (15-50 min) and short times (88-96%). The synthesis was performed through the one-pot, three-component reaction of aryl aldehydes, dimedone, and 6-amino-1,3-dimethyluracil in the absence of solvent. Research Highlights A novel magnetic nanocatalyst namely [Fe3O4@SiO2@RNMe2-SO3H][CF3CO2] (FSRNSC) was prepared. Full characterization of FSRNSC using FT-IR, EDS, elemental mapping, FE-SEM, XRD, VSM, TG and DTG analyses was aperformed. Application of FSRNSC for the construction of pyrimido[4,5-b]quinolones was done.. Producing pyrimido[4,5-b]quinolines in short times with high yields were advantages of this method. Reusability of the catalyst was investigated.