OICC Press Iranian Journal of Catalysis 2345-4865 6 4 2024 02 03 Eggshell-supported-Cu(II) salophen complex: An efficient and green catalyst for synthesis of propargylamines under solvent-free conditions EN Mohammad Bakherad School of Chemistry, Shahrood University of Technology, Shahrood 3619995161, Iran 0000-0003-4093-8944 Ali Keivanloo Faculty of Chemistry, Shahrood University of Technology, Shahrood, Iran. Amir Hossein Amin Faculty of Chemistry, Shahrood University of Technology, Shahrood, Iran. Raheleh Doosti School of Chemistry, Shahrood University of Technology, Shahrood, Iran. Ommolbanin Hoseini School of Chemistry, Shahrood University of Technology, Shahrood, Iran. Journal Article 2024 02 03 In this report, the synthesis, characterization, and application of the eggshell-supported-Cu(II) salophen complex, as a novel and heterogeneous catalyst, is described. The catalyst is characterized by the UV, XRD, FT-IR, and SEM techniques. The eggshell-supported-Cu(II) salophen complex is a versatile, green, inexpensive, and simple catalyst used for the multi-component reactions (MCRs) of terminal alkynes, aldehydes, and secondary amines to give the corresponding propargylamines at 80 °C under the solvent-free conditions. The proposed methodology offers several advantages such as excellent product yield, simple procedure, and mild conditions. On the other hand, the synthesized catalyst could be removed from the reaction mixture by simple filtration, and reused for up to six runs.