OICC Press Iranian Journal of Catalysis 2345-4865 5 4 2024 02 03 Et3N as a catalyst for the synthesis of indeno[1,2-b]chromene derivatives via three-component condensation reaction EN Ali Sadeghi Department of Chemistry, Jouybar Branch, Islamic Azad University, Jouybar, Iran. Ali Hossein Rezayan Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran. Ali Farajtabar Department of Chemistry, Jouybar Branch, Islamic Azad University, Jouybar, Iran. Journal Article 2024 02 03 Functionalized indeno[1,2-b]chromene derivatives have been synthesized via condensation reaction of 1H-indene-1,3(2H)-dione with benzaldehyde and cyclization with 2-hydroxynaphthalene-1,4-dione in the presence of a catalytic amount of triethylamine (Et3N) in EtOH at room temperature. It was observed that benzaldehyde bearing electron donating group gave high yield of product, whereas, benzaldehyde having electronic withdrawing substituent does not participate in this reaction. The structures were confirmed spectroscopically (IR, 1H- and 13C-NMR, and Mass). A plausible mechanism for this reaction is proposed (Scheme 2). Good yields and easy purification are the main advantages of the present method. Products of these reactions have structural similarity to naturally occurring pyranokunthone B, lambertellin, β-lapachone, and α-xiloidone.