OICC Press Iranian Journal of Catalysis 2345-4865 2 4 2024 02 03 Nicotine-based ionic liquid: as a green catalyst for pyridine-catalyzed Huisgen reaction EN Ahmed Ali Hullio Dr. M.A Kazi Institute of chemistry, University of Sindh Jamshoro-76080, Pakistan. Ghulam Murtaza Mastoi Dr. M.A Kazi Institute of chemistry, University of Sindh Jamshoro-76080, Pakistan. Journal Article 2024 02 03 Nicotine-based ionic liquid has been used as a green catalyst for pyridine-catalyzed Huisgen reaction. It promoted addition of dimethylacetylenedicarboxylate to aldehydes or N-tosyl imines leading to efficient synthesis of 2-benzoylfumarates and 1-azadienes respectively under pyridine free odorless ionic liquid conditions. The improved results were obtained in terms of enhanced yields, with minimal work up.