OICC Press Iranian Journal of Catalysis 2345-4865 12 4 2023 12 22 Nano-cellulose-OSnCl4-x: Green and natural-based renewable nanocatalyst for one-pot synthesis of 2-amino-3-phenylsulfonyl-4H-pyran derivatives 10.30495/ijc.2022.1958448.1933 EN Sayed Rasul Shafe-Mehrabadi Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran 0000-0001-7699-8776 Bahareh Sadeghi Department of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran Mohammad Hossein Mosslemin Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran Saeedeh Hashemian Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran Journal Article 2023 12 22 A highly efficient, eco-friendly procedure has been proposed for the synthesis of 2-amino-3-phenylsulfonyl-4H-pyran derivatives via nano-cellulose-OSnCl4-x catalyst prepared from cotton as support treated with tin tetrachloride (SnCl4). This catalyst is characterized by FT-IR, FESEM, TEM, TGA, and EDX. The TEM results confirmed the size of the nano-cellulose-OSnCl4-x catalyst was below 30 nm. The efficiency of this solid acid catalyst was investigated in one-pot, three-component condensation reactions with aromatic aldehydes, dimedone, and phenylsulfonylacetonitrile under reflux conditions. As a result, 2-amino-3-phenylsulfonyl-4H-pyran derivatives were produced under facile conditions in high yield (84-95%) and high rate (30-50 min) using nano-cellulose-OSnCl4-x as a recyclable catalyst. Highlights Preparation, characterization and application of nano-cellulose-OSnCl4-x as a green and natural-based nanocatalyst Nano-cellulose-OSnCl4-x as a renewable nanocatalyst for one-pot synthesis of 2-amino-3-phenylsulfonyl-4H-pyran derivatives Synthesis of new derivatives of 2-amino-7,8-dihydro-7,7-dimethyl-4-phenyl-3-(phenylsulfonyl)-4H-chromen-5(6H)-one Prominent among the advantages of this method are working simplicity, mild reaction condition, short reaction times, higher yields, and environmental friendliness