OICC Press Iranian Journal of Catalysis 2345-4865 12 2 2022 05 08 Pistachio peel biomass derived magnetic nanoparticles Fe3O4@C-SO3H: a highly efficient catalyst for the synthesis of isoxazole-5(4H)-one, 1-amido alkyl-2-naphthol, pyrano[2,3-c]pyrazole and 2,3-dihydro quinazoline-4(1H)-one derivatives 10.30495/ijc.2022.690999 EN Fatemeh Ghorbani School of Chemistry, Damghan University Damghan, Iran 0000-0003-2217-4346 Seied Ali Pourmousavi Institute of Biological Science, Damghan University Damghan, Iran 0000-0003-2217-4346 Journal Article 2022 05 08 Green chemistry has fostered research on recyclable, insoluble, and easily separable heterogeneous catalysts. Carbon materials are widely used for renewable energy and environmental studies. Here, we used green Pistachio peel, a biomass waste for the synthesis of magnetic carbon-based solid acid (Fe3O4@C-SO3H) by carbonization and sulfonation. The physicochemical properties of the nanocatalyst were characterized using XRD, FT-IR, FE-SEM, TGA, VSM, and TEM. The catalytic activity of Fe3O4@C-SO3H was investigated in the synthesis of isoxazole-5(4H)-one, 1-amido alkyl-2-naphthol, pyrano[2,3-c]pyrazole, and 2,3-dihydro quinazoline-4(1H)-one derivative, and some of the synthesized compounds were screened for their anti-microbial activity. Furthermore, the recovery and reuse of the catalyst were demonstrated six times without detectible loss inactivity. The concentration of H+ loaded on the Fe3O4@C-SO3H was reported to be 1.3 mmol g-1. The well-defined Fe3O4@C-SO3H core–shell heterostructures exhibited high stability, efficient recyclability (6 cycles).