OICC Press Iranian Journal of Catalysis 2345-4865 10 3 2024 02 03 One-pot three-component synthesis of tetrahydrobenzo[b]pyrans in the presence of Ni0.5Cu0.5Fe2O4 magnetic nanoparticles under microwave irradiation in solvent-free conditions EN Hamideh Ahankar Department of Chemistry, Abhar Branch, Islamic Azad University, P. O. Box 22, Abhar, Iran. 0000-0002-2717-8920 Saeid Taghavi Fardood Department of Chemistry, University of Zanjan, P O Box 45195-313, Zanjan, Iran. 0000-0002-0645-1393 Ali Ramazani Department of Chemistry, Faculty of Science, University of Zanjan, 45371-38791 Zanjan, Iran Journal Article 2024 02 03 Ni0.5Cu0.5Fe2O4 magnetic nanoparticles using Arabic gel (AG) as a reducing and stabilizing agent was prepared by the sol-method. The catalyst identification was performed using Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), and vibrating sample magnetometer (VSM). The magnetic analysis showed that the Ni0.5Cu0.5Fe2O4 had a ferromagnetic behavior with a saturation magnetization of 31.22 emu/g at room temperature. Then, Ni0.5Cu0.5Fe2O4 magnetic nanoparticles were applied as a green, convenient, effective and reusable catalyst for the one-pot three-component synthesis of tetrahydrobenzo[b]pyrans in good to excellent yields. It should be noted, the nanocatalyst is separated by a magnet was used several times and it was as efficient as ever.