An effective, novel, and recyclable γ-Fe2O3@MoS2@Znas magnetic nanocatalyst in the unprecedented synthesisof mono- and bis-triazoles
- Department of Chemistry, University Campus 2, University of Guilan, Rasht, Iran
- Department of Organic Chemistry, Faculty of Chemistry, University of Guilan, P.O. Box 41335-1914, Rasht, Iran
Received: 2024-05-16
Revised: 2024-07-15
Accepted: 2024-09-08
Published 2024-11-23
Copyright (c) 2024 @Authors

This work is licensed under a Creative Commons Attribution 4.0 International License.
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Abstract
ABSTRACT
Triazoles are an important group that have active biological properties, and their synthetic platform and reactions have been fully investigated by many synthetic and medicinal chemists during the recent years. Magnetic nanocatalysts have recently been used in the design of many reactions, so in this method, an efficient, novel, and recyclable magnetic nanocatalyst γ-Fe2O3@MoS2@Zn was synthesized by the reaction of premade g-Fe2O3@MoS2 and ZnCl2 to furnish the desired nanocatalyst which was characterized by using FT-IR, XRD, SEM, EDX, TEM, mapping and VSM techniques. The catalyst was used in the synthesis of mono- and bis-triazoles by the reaction of thiosemicarbazide or butane-1,4-diyl-bis(hydrazinecarbimidothioate) with various arylaldehydes at room temperature and in ethanol/water (50:50) as solvent. This novel protocol gave the desired products excellent yields (92-96%) and lower reaction times (15-20 min). The synthesized magnetic nanoparticles were comfortability separated from the reaction mixture by means of an external magnet and employed in six consecutive runs without any significant changes in its catalytic activity. The advantages of this current method are short reaction time, excellent efficiency, use of green solvent, magnetic nanocatalyst, and cost-effectiveness.
Research Highlights
- A novel Zn supported magnetic nanocatalyst was synthesized.
- The synthesized nanocatalyst was used in a benign and practical synthesis of a series of densely functionalized mono- and bis-triazoles.
- The catalyst was recycled and reused in 6 consecutive runs without significant decrease in its catalytic activities.
Keywords
- Bis-triazole,
- Nanoparticle,
- Triazole,
- γ-Fe2O3,
- MoS2,
- Zinc
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