Silica gel: A very cheap, reusable, and efficient catalyst for green preparation of some bis-4-hydroxycoumarin on water
- Department of Chemistry, Yasouj University, Yasouj, Zip Code: 75918-74831 P.O. Box 353, Iran.
- Young and Reasearcers Elite, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
Abstract
Silica gel has been used for synthesis of biscoumarin derivatives starting from 4-hydroxycoumarin and aryl aldehydes. The reaction conditions are completely in agreement with green chemistry principles including sing water as media and a recyclable and safe catalyst. This method is also simple and inexpensive and leads to high yield of products in short reaction times.