A green, efficient, and rapid procedure for the synthesis of pyrano[3,2-c] quinoline and pyrano[3,2-c]pyridone derivatives catalyzed by [BMIm]Cl
- Young Researchers and Elites Club, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
- Young Researchers and Elites Club, Rasht Branch, Islamic Azad University, Rasht, Iran.
- Chemistry Department, University of Guilan, P.O. Box 41335-19141, Rasht, Iran.
- Department of Applied Chemistry, Ardabil Branch, Islamic Azad University, Ardabil, 56157, I.R. Iran.
Abstract
A highly practical and efficient preparation of pyrano[3,2-c]pyridone and pyrano[3,2-c]quinoline derivatives was developed via an ionic liquid mediated and promoted multi-component reaction of malononitrile, aldehyde, and 4-hydroxyquinolin-2(1H)-one or 4-hydroxy-6-methylpyridin-2(1H)-one. The combinatorial syntheses were achieved for the first time without applying extra activation energy at ambient temperature while making use of [BMIm]Cl as a catalyst solvent.