Brönsted acidic ionic liquid ([Hmim][HSO4]) as a green, efficient and reusable catalyst for the tetrahydropyranylation of alcohols
- Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran.
- Department of Pharmacology, University of Wisconsin, Medical School, 1300 University Avenue, Madison, 53706-1532, WI, USA.
- Department of Organic Chemistry, Faculty of Chemistry, Alzahra University, Tehran, Iran
Abstract
A simple and mild method for tetrahydropyranylation of alcohols is reported at room temperature using a catalytic amount of 3-methylimidazolinium hydrogensulfate([Hmim]HSO4) as a green, efficient and reusable catalyst. Using solvent-free conditions, non-toxic and inexpensive materials, modest and clean work-up, short reaction times and high yields of the products are the advantages of this method.