10.1007/s40089-022-00385-x

Recent advancements in Janus nanoparticle-based biosensing platforms

  1. National Centre for Nanoscience and Nanotechnology, University of Mumbai, Mumbai, IN

Published in Issue 2022-11-19

How to Cite

Karadkar, S., Tiwari, A., & Chaskar, A. C. (2022). Recent advancements in Janus nanoparticle-based biosensing platforms. International Nano Letters, 13(2 (June 2023). https://doi.org/10.1007/s40089-022-00385-x

PDF views: 286

Abstract

Abstract Nanoparticles have aided in the development of nano-based sensors for diagnostic applications. However, use of nanoparticles in the development of sensing devices for multiple analyte detection is constrained due to their inability to detect several analytes with a single type of nanoparticle. The term “Janus particle” refers to micro or nanoscale particles that have been divided into sections or compartments, each of which has a distinct set of chemical or physical properties, producing multifunctional particles endowed with distinctive qualities. Furthermore, Janus particles have the ability to perform multiple functions within a single particle at the same time, with no interference from adjacent sections. This review focuses on the use of Janus particles in the fabrication of biosensors as well as in the investigation of various properties endowed by these Janus particles for their use as biosensors. It also discusses the various types of Janus particle-based biosensors that are currently available. Finally, the limitations of Janus particles in sensor technologies and their future scope have been discussed. Graphical abstract

Keywords

  • Janus nanoparticle,
  • Biosensing,
  • Point of care

References

  1. Mitchell et al. (2021) Engineering precision nanoparticles for drug delivery 20(2) (pp. 101-124) https://doi.org/10.1038/s41573-020-0090-8
  2. Mohammadi Ziarani et al. (2019) The role of hollow magnetic nanoparticles in drug delivery 9(43) (pp. 25094-25106) https://doi.org/10.1039/c9ra01589b
  3. Chen et al. (2019) Nanomachines and other caps on mesoporous silica nanoparticles for drug delivery 52(6) (pp. 1531-1542) https://doi.org/10.1021/acs.accounts.9b00116
  4. Yin (2019) A highly sensitivity and selectivity Pt-SnO2 nanoparticles for sensing applications at extremely low level hydrogen gas detection (pp. 229-236) https://doi.org/10.1016/j.jallcom.2019.07.081
  5. Gloag et al. (2019) Advances in the application of magnetic nanoparticles for sensing 31(48) (pp. 1-26) https://doi.org/10.1002/adma.201904385
  6. Chu (2019) Nanoparticle-based LDI-MS immunoassay for the multiple diagnosis of viral infections 4(6) (pp. 1543-1551) https://doi.org/10.1021/acssensors.9b00054
  7. Zhang et al. (2019) 3D carbon nanosphere and gold nanoparticle-based voltammetric cytosensor for cell line A549 and for early diagnosis of non-small cell lung cancer cells 186(1) (pp. 2-8) https://doi.org/10.1007/s00604-018-3160-4
  8. Dissanayake et al. (2019) Highly sensitive plasmonic metal nanoparticle-based sensors for the detection of organophosphorus pesticides (pp. 218-227) https://doi.org/10.1016/j.talanta.2019.03.042
  9. Rahman et al. (2019) Development of an efficient phenolic sensor based on facile Ag2O/Sb2O3 nanoparticles for environmental safety 1(2) (pp. 696-705) https://doi.org/10.1039/c8na00034d
  10. Wu (2019) Surface-imprinted gold nanoparticle-based surface-enhanced raman scattering for sensitive and specific detection of patulin in food samples 12(7) (pp. 1648-1657) https://doi.org/10.1007/s12161-019-01498-4
  11. Li et al. (2019) Nanoparticle-based sensors for food contaminants (pp. 74-83) https://doi.org/10.1016/j.trac.2019.01.012
  12. Ular et al. (2018) Diaminocyclohexane-functionalized/thioglycolic acid-modified gold nanoparticle-based colorimetric sensing of trinitrotoluene and tetryl 3(11) (pp. 2335-2342) https://doi.org/10.1021/acssensors.8b00709
  13. Üzer et al. (2014) 4-aminothiophenol functionalized gold nanoparticle-based colorimetric sensor for the determination of nitramine energetic materials 86(1) (pp. 351-356) https://doi.org/10.1021/ac4032725
  14. Gui et al. (2009) Detection and discrimination of low concentration explosives using MOS nanoparticle sensors 164(2–3) (pp. 1030-1035) https://doi.org/10.1016/j.jhazmat.2008.09.011
  15. Charbgoo et al. (2017) Bio-sensing applications of cerium oxide nanoparticles: advantages and disadvantages (pp. 33-43) https://doi.org/10.1016/j.bios.2017.04.037
  16. Su et al. (2019) Janus particles: design, preparation, and biomedical applications https://doi.org/10.1016/j.mtbio.2019.100033
  17. Sun et al. (2017) Multitarget sensing of glucose and cholesterol based on Janus hydrogel microparticles 92(February) (pp. 81-86) https://doi.org/10.1016/j.bios.2017.02.008
  18. Xie et al. (2012) One-step fabrication of polymeric Janus nanoparticles for drug delivery 28(9) (pp. 4459-4463) https://doi.org/10.1021/la2042185
  19. Safaie and Ferrier (2020) Janus nanoparticle synthesis: overview, recent developments, and applications https://doi.org/10.1063/5.0003329
  20. Jiang and Granick (2007) Janus balance of amphiphilic colloidal particles https://doi.org/10.1063/1.2803420
  21. Walther and Müller (2008) Janus particles 4(4) (pp. 663-668) https://doi.org/10.1039/b718131k
  22. Gheisari (2021) Janus nanoparticles: an efficient intelligent modern nanostructure for eradicating cancer 53(4) (pp. 592-603) https://doi.org/10.1080/03602532.2021.1878530
  23. Lattuada and Hatton (2011) Synthesis, properties and applications of Janus nanoparticles 6(3) (pp. 286-308) https://doi.org/10.1016/j.nantod.2011.04.008
  24. Lazarides et al. (2000) Optical properties of metal nanoparticles and nanoparticle aggregates important in biosensors 529(1–3) (pp. 59-63) https://doi.org/10.1016/S0166-1280(00)00532-7
  25. Anker et al. (2003) Aspherical magnetically modulated optical nanoprobes (MagMOONs) 93(102) (pp. 6698-6700) https://doi.org/10.1063/1.1556926
  26. Xing (2019) Construction strategy for ratiometric fluorescent probe based on Janus silica nanoparticles as a platform toward intracellular pH detection 205(May) https://doi.org/10.1016/j.talanta.2019.06.021
  27. Russell et al. (2019) Multifunctional motion-to-color janus transducers for the rapid detection of sepsis biomarkers in whole blood https://doi.org/10.1016/j.bios.2019.111346
  28. Soylemez et al. (2015) Electrochemical and optical properties of a conducting polymer and its use in a novel biosensor for the detection of cholesterol (pp. 425-433) https://doi.org/10.1016/j.snb.2015.02.045
  29. Zhang (2021) A fast and general approach to produce a carbon coated Janus metal/oxide hybrid for catalytic water splitting 9(12) (pp. 7606-7616) https://doi.org/10.1039/d0ta12021a
  30. Iqbal (2018) A facile fabrication route for binary transition metal oxide-based Janus nanoparticles for cancer theranostic applications 11(10) (pp. 5735-5750) https://doi.org/10.1007/s12274-017-1628-x
  31. Sanchez-Vazquez et al. (2017) Electrosprayed Janus particles for combined photo-chemotherapy 18(5) (pp. 1460-1468) https://doi.org/10.1208/s12249-016-0638-4
  32. Karshalev (2019) Micromotors for active delivery of minerals toward the treatment of iron deficiency anemia 19(11) (pp. 7816-7826) https://doi.org/10.1021/acs.nanolett.9b02832
  33. Feng (2019) Magnetic Janus particles as a multifunctional drug delivery system for paclitaxel in efficient cancer treatment 104(June) https://doi.org/10.1016/j.msec.2019.110001
  34. Le et al. (2019) Janus particles: recent advances in the biomedical applications (pp. 6749-6777) https://doi.org/10.2147/IJN.S169030
  35. Chen (2020) Click-grafting of cardanol onto mesoporous silica/silver Janus particles for enhanced hemostatic and antibacterial performance 3(12) (pp. 9054-9064) https://doi.org/10.1021/acsabm.0c01267
  36. Dehghani et al. (2020) A pH-controlled approach to fabricate electrolyte/non-electrolyte janus particles with low cytotoxicity as carriers of DOX 249(March) https://doi.org/10.1016/j.matchemphys.2020.123000
  37. Li (2017) Degradation-restructuring induced anisotropic epitaxial growth for fabrication of asymmetric diblock and triblock mesoporous nanocomposites 29(30) (pp. 1-8) https://doi.org/10.1002/adma.201701652
  38. Ye (2019) Fabrication of self-propelled micro- and nanomotors based on Janus structures 25(37) (pp. 8663-8680) https://doi.org/10.1002/chem.201900840
  39. Tan and Chen (2019) Mask-less preparation of Janus particles through ultraviolet irradiation on hydrophobic particles assembled at the air-water interface (pp. 285-292) https://doi.org/10.1016/j.jcis.2019.03.081
  40. Wang et al. (2020) Fluorescent self-propelled covalent organic framework as a microsensor for nitro explosive detection https://doi.org/10.1016/j.apmt.2019.100550
  41. Sun et al. (2016) Controlled production of size-tunable Janus droplets for submicron particle synthesis using an electrospray microfluidic chip 6(15) (pp. 12042-12047) https://doi.org/10.1039/c5ra24531a
  42. Mou et al. (2013) Oppositely charged twin-head electrospray: a general strategy for building Janus particles with controlled structures 5(5) (pp. 2055-2064) https://doi.org/10.1039/c2nr33523a
  43. Wang et al. (2019) Droplet-based microfluidic synthesis of (Au nanorod@Ag)-polyaniline Janus nanoparticles and their application as a surface-enhanced Raman scattering nanosensor for mercury detection 11(31) (pp. 3966-3973) https://doi.org/10.1039/c9ay01213c
  44. Kumar (2019) Structural evolution of iron–copper (Fe–Cu) bimetallic Janus nanoparticles during solidification: an atomistic investigation https://doi.org/10.1021/acs.jpcc.9b08411
  45. Jiang et al. (2010) Janus particle synthesis and assembly 22(10) (pp. 1060-1071) https://doi.org/10.1002/adma.200904094
  46. Paniagua (2019) Amperometric aptasensor for carcinoembryonic antigen based on the use of bifunctionalized Janus nanoparticles as biorecognition-signaling element (pp. 84-91) https://doi.org/10.1016/j.aca.2019.02.015
  47. Yang (2019) A Label-free aptasensor based on Aptamer/NH2 Janus particles for ultrasensitive electrochemical detection of Ochratoxin A (pp. 310-316) https://doi.org/10.1016/j.talanta.2019.02.015
  48. Zhou (2018) Electrochemical sensor for determination of ractopamine based on aptamer/octadecanethiol Janus particles (pp. 204-210) https://doi.org/10.1016/j.snb.2018.08.110
  49. Kong et al. (2019) Micromotor-assisted human serum glucose biosensing 91(9) (pp. 5660-5666) https://doi.org/10.1021/acs.analchem.8b05464
  50. Pacheco et al. (2018) Sensitive monitoring of enterobacterial contamination of food using self-propelled Janus microsensors 90(4) (pp. 2912-2917) https://doi.org/10.1021/acs.analchem.7b05209
  51. Pacheco et al. (2020) Engineering Janus micromotors with WS2 and affinity peptides for turn-on fluorescent sensing of bacterial lipopolysaccharides https://doi.org/10.1016/j.bios.2020.112286
  52. de La Asunción-Nadal et al. (2020) Chalcogenides-based tubular micromotors in fluorescent assays 92(13) (pp. 9188-9193) https://doi.org/10.1021/acs.analchem.0c01541
  53. Li et al. (2021) Janus emulsion biosensors for Anti-SARS-CoV-2 spike antibody 7(7) (pp. 1166-1175) https://doi.org/10.1021/acscentsci.1c00173
  54. Li et al. (2020) Fluorescent Janus emulsions for biosensing of Listeria monocytogenes 117(22) (pp. 1-8) https://doi.org/10.1073/pnas.2002623117
  55. Yue Chen et al. (2018) Direct colorimetric detection of aspartic acid in rat brain based on oriented aggregation of Janus gold nanoparticle (pp. 668-675) https://doi.org/10.1016/j.snb.2018.08.008
  56. Yang (2014) Superhydrophobic surface enhanced Raman scattering sensing using Janus particle arrays realized by site-specific electrochemical growth 2(3) (pp. 542-547) https://doi.org/10.1039/c3tc31635a
  57. Petry et al. (2003) Raman spectroscopy—a prospective tool in the life sciences 4(1) (pp. 14-30) https://doi.org/10.1002/cphc.200390004
  58. Zhang et al. (2019) Design of Gold nanorods Janus membrane for efficient and high-sensitive surface-enhanced Raman scattering and tunable surface plasmon resonance 721(February) (pp. 117-122) https://doi.org/10.1016/j.cplett.2019.02.035
  59. Park et al. (2018) Tunable aggregation of gold-silica janus nanoparticles to enable contrast-enhanced multiwavelength photoacoustic imaging in vivo 10(32) (pp. 15365-15370) https://doi.org/10.1039/c8nr03973a
  60. Beltrán-Gastélum (2019) Rapid detection of AIB1 in breast cancer cells based on aptamer-functionalized nanomotors 20(23) (pp. 3177-3180) https://doi.org/10.1002/cphc.201900844
  61. Demirörs et al. (2018) Active cargo transport with Janus colloidal shuttles using electric and magnetic fields 14(23) (pp. 4741-4749) https://doi.org/10.1039/c8sm00513c
  62. Yuan et al. (2020) Janus micromotors coated with 2D nanomaterials as dynamic interfaces for (Bio)-sensing https://doi.org/10.1021/acsami.0c15389
  63. Qualliotine et al. (2019) Acoustic nanomotors for detection of human papillomavirus-associated head and neck cancer 161(5) (pp. 814-822) https://doi.org/10.1177/0194599819866407